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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRODH2 All Species: 9.7
Human Site: S72 Identified Species: 16.41
UniProt: Q9UF12 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UF12 NP_067055.1 536 58871 S72 N L P W C G G S Q G P R M L R
Chimpanzee Pan troglodytes XP_524461 536 58825 S72 N L P W C G G S Q G P R M L R
Rhesus Macaque Macaca mulatta XP_001112278 458 50173 L18 Q H S G H H Y L G G G G S N C
Dog Lupus familis XP_541686 567 62920 R70 S Q R L L G S R L S G A F L R
Cat Felis silvestris
Mouse Mus musculus Q8VCZ9 456 50705 T16 Y G P S K P S T G G W Q P L R
Rat Rattus norvegicus Q2V057 456 50984 T16 Y G H S K P S T G G W Q P L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6PAY6 466 52311 P25 R V W P T L P P S C S P H S T
Zebra Danio Brachydanio rerio NP_001002391 465 52716 R25 P S P A A Y L R F E D P Q A F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q04499 681 77135 S92 S S E T V K R S M K Q E S S Q
Honey Bee Apis mellifera XP_395275 528 60938 D63 F G V K P I L D Y S V E E D I
Nematode Worm Caenorhab. elegans O45228 616 69804 N109 M R R V L G K N L F K K T L K
Sea Urchin Strong. purpuratus XP_782069 402 44953
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92983 499 54937 S59 H P K P T E Q S H D G L D L S
Baker's Yeast Sacchar. cerevisiae P09368 476 53253 N36 S K T P T H S N T A A N L M V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 78.7 69.3 N.A. 69.7 69.2 N.A. N.A. N.A. 46.4 41 N.A. 28.3 28.5 26.9 26.4
Protein Similarity: 100 99.6 81.1 73.9 N.A. 75.5 75 N.A. N.A. N.A. 60 55.5 N.A. 45.6 46.8 43 43.4
P-Site Identity: 100 100 6.6 20 N.A. 26.6 20 N.A. N.A. N.A. 0 6.6 N.A. 6.6 0 13.3 0
P-Site Similarity: 100 100 6.6 26.6 N.A. 40 33.3 N.A. N.A. N.A. 6.6 6.6 N.A. 20 0 33.3 0
Percent
Protein Identity: N.A. N.A. N.A. 25.9 21.8 N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 38.6 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 0 0 0 8 8 8 0 8 0 % A
% Cys: 0 0 0 0 15 0 0 0 0 8 0 0 0 0 8 % C
% Asp: 0 0 0 0 0 0 0 8 0 8 8 0 8 8 0 % D
% Glu: 0 0 8 0 0 8 0 0 0 8 0 15 8 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 8 8 0 0 8 0 8 % F
% Gly: 0 22 0 8 0 29 15 0 22 36 22 8 0 0 0 % G
% His: 8 8 8 0 8 15 0 0 8 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 8 8 8 15 8 8 0 0 8 8 8 0 0 8 % K
% Leu: 0 15 0 8 15 8 15 8 15 0 0 8 8 50 0 % L
% Met: 8 0 0 0 0 0 0 0 8 0 0 0 15 8 0 % M
% Asn: 15 0 0 0 0 0 0 15 0 0 0 8 0 8 0 % N
% Pro: 8 8 29 22 8 15 8 8 0 0 15 15 15 0 0 % P
% Gln: 8 8 0 0 0 0 8 0 15 0 8 15 8 0 8 % Q
% Arg: 8 8 15 0 0 0 8 15 0 0 0 15 0 0 36 % R
% Ser: 22 15 8 15 0 0 29 29 8 15 8 0 15 15 8 % S
% Thr: 0 0 8 8 22 0 0 15 8 0 0 0 8 0 8 % T
% Val: 0 8 8 8 8 0 0 0 0 0 8 0 0 0 8 % V
% Trp: 0 0 8 15 0 0 0 0 0 0 15 0 0 0 0 % W
% Tyr: 15 0 0 0 0 8 8 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _