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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRODH2
All Species:
4.55
Human Site:
S99
Identified Species:
7.69
UniProt:
Q9UF12
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UF12
NP_067055.1
536
58871
S99
S
R
G
W
Q
S
L
S
F
D
G
G
A
F
H
Chimpanzee
Pan troglodytes
XP_524461
536
58825
S99
S
R
G
W
Q
S
L
S
F
D
G
G
A
F
H
Rhesus Macaque
Macaca mulatta
XP_001112278
458
50173
E45
L
V
N
L
L
P
P
E
H
L
P
W
C
G
G
Dog
Lupus familis
XP_541686
567
62920
V97
A
E
E
V
K
G
C
V
Q
Q
L
Q
T
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCZ9
456
50705
V43
E
L
A
R
A
L
L
V
L
R
L
C
A
W
P
Rat
Rattus norvegicus
Q2V057
456
50984
V43
E
L
A
R
A
L
L
V
L
R
L
C
A
W
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PAY6
466
52311
L52
S
D
G
G
V
F
K
L
K
S
S
W
E
V
A
Zebra Danio
Brachydanio rerio
NP_001002391
465
52716
F52
G
V
F
R
L
C
S
F
P
V
L
V
N
N
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04499
681
77135
N119
D
P
L
D
V
S
F
N
D
P
I
A
A
F
K
Honey Bee
Apis mellifera
XP_395275
528
60938
E90
S
V
S
E
A
G
D
E
K
R
E
G
P
L
K
Nematode Worm
Caenorhab. elegans
O45228
616
69804
V136
E
E
E
V
R
H
V
V
E
K
L
R
N
Y
G
Sea Urchin
Strong. purpuratus
XP_782069
402
44953
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92983
499
54937
V86
D
L
L
R
S
T
A
V
L
H
A
A
A
I
G
Baker's Yeast
Sacchar. cerevisiae
P09368
476
53253
N63
M
A
P
P
N
S
I
N
F
L
Q
T
L
P
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
78.7
69.3
N.A.
69.7
69.2
N.A.
N.A.
N.A.
46.4
41
N.A.
28.3
28.5
26.9
26.4
Protein Similarity:
100
99.6
81.1
73.9
N.A.
75.5
75
N.A.
N.A.
N.A.
60
55.5
N.A.
45.6
46.8
43
43.4
P-Site Identity:
100
100
0
0
N.A.
13.3
13.3
N.A.
N.A.
N.A.
13.3
0
N.A.
20
13.3
0
0
P-Site Similarity:
100
100
0
13.3
N.A.
20
20
N.A.
N.A.
N.A.
13.3
0
N.A.
26.6
13.3
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
21.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
0
22
0
8
0
0
0
8
15
43
0
8
% A
% Cys:
0
0
0
0
0
8
8
0
0
0
0
15
8
0
8
% C
% Asp:
15
8
0
8
0
0
8
0
8
15
0
0
0
0
0
% D
% Glu:
22
15
15
8
0
0
0
15
8
0
8
0
8
0
0
% E
% Phe:
0
0
8
0
0
8
8
8
22
0
0
0
0
22
0
% F
% Gly:
8
0
22
8
0
15
0
0
0
0
15
22
0
8
29
% G
% His:
0
0
0
0
0
8
0
0
8
8
0
0
0
0
15
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
8
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
8
0
15
8
0
0
0
0
22
% K
% Leu:
8
22
15
8
15
15
29
8
22
15
36
0
8
15
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
15
0
0
0
0
15
8
0
% N
% Pro:
0
8
8
8
0
8
8
0
8
8
8
0
8
8
15
% P
% Gln:
0
0
0
0
15
0
0
0
8
8
8
8
0
0
0
% Q
% Arg:
0
15
0
29
8
0
0
0
0
22
0
8
0
0
0
% R
% Ser:
29
0
8
0
8
29
8
15
0
8
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
8
8
0
0
% T
% Val:
0
22
0
15
15
0
8
36
0
8
0
8
0
8
0
% V
% Trp:
0
0
0
15
0
0
0
0
0
0
0
15
0
15
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _