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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRODH2
All Species:
6.67
Human Site:
T34
Identified Species:
11.28
UniProt:
Q9UF12
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UF12
NP_067055.1
536
58871
T34
S
N
V
F
N
N
T
T
A
F
P
I
L
R
G
Chimpanzee
Pan troglodytes
XP_524461
536
58825
T34
S
N
V
F
N
N
T
T
A
F
P
I
L
R
G
Rhesus Macaque
Macaca mulatta
XP_001112278
458
50173
Dog
Lupus familis
XP_541686
567
62920
R39
K
G
T
G
E
L
T
R
A
L
L
V
L
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCZ9
456
50705
Rat
Rattus norvegicus
Q2V057
456
50984
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PAY6
466
52311
Zebra Danio
Brachydanio rerio
NP_001002391
465
52716
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04499
681
77135
A52
T
S
I
A
G
E
G
A
A
S
E
S
T
R
G
Honey Bee
Apis mellifera
XP_395275
528
60938
Y34
K
L
M
R
A
S
F
Y
G
H
F
V
A
G
E
Nematode Worm
Caenorhab. elegans
O45228
616
69804
T35
K
R
C
Y
S
G
D
T
G
K
P
Y
D
C
T
Sea Urchin
Strong. purpuratus
XP_782069
402
44953
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92983
499
54937
A30
V
G
P
P
T
V
T
A
S
T
A
V
V
P
E
Baker's Yeast
Sacchar. cerevisiae
P09368
476
53253
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
78.7
69.3
N.A.
69.7
69.2
N.A.
N.A.
N.A.
46.4
41
N.A.
28.3
28.5
26.9
26.4
Protein Similarity:
100
99.6
81.1
73.9
N.A.
75.5
75
N.A.
N.A.
N.A.
60
55.5
N.A.
45.6
46.8
43
43.4
P-Site Identity:
100
100
0
26.6
N.A.
0
0
N.A.
N.A.
N.A.
0
0
N.A.
20
0
13.3
0
P-Site Similarity:
100
100
0
33.3
N.A.
0
0
N.A.
N.A.
N.A.
0
0
N.A.
40
20
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
21.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
15
29
0
8
0
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
8
8
0
0
0
0
8
0
0
0
15
% E
% Phe:
0
0
0
15
0
0
8
0
0
15
8
0
0
0
0
% F
% Gly:
0
15
0
8
8
8
8
0
15
0
0
0
0
8
22
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
15
0
0
0
% I
% Lys:
22
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
8
0
0
0
8
8
0
22
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
15
15
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
8
0
0
0
0
0
0
22
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
0
0
0
8
0
0
0
0
0
29
0
% R
% Ser:
15
8
0
0
8
8
0
0
8
8
0
8
0
0
0
% S
% Thr:
8
0
8
0
8
0
29
22
0
8
0
0
8
0
8
% T
% Val:
8
0
15
0
0
8
0
0
0
0
0
22
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _