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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRODH2
All Species:
7.88
Human Site:
T420
Identified Species:
13.33
UniProt:
Q9UF12
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UF12
NP_067055.1
536
58871
T420
R
C
L
E
L
M
L
T
H
V
A
R
H
G
P
Chimpanzee
Pan troglodytes
XP_524461
536
58825
T420
R
C
L
E
L
M
L
T
H
V
A
R
H
G
P
Rhesus Macaque
Macaca mulatta
XP_001112278
458
50173
A351
D
A
E
A
A
H
R
A
G
L
A
F
G
V
K
Dog
Lupus familis
XP_541686
567
62920
E416
S
I
P
Y
G
S
L
E
E
V
I
P
Y
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCZ9
456
50705
H349
M
L
R
C
V
S
N
H
G
P
P
C
H
L
M
Rat
Rattus norvegicus
Q2V057
456
50984
H349
M
L
R
R
V
S
N
H
G
P
R
C
H
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PAY6
466
52311
Q358
K
M
L
D
L
I
G
Q
N
G
Q
R
H
N
L
Zebra Danio
Brachydanio rerio
NP_001002391
465
52716
T358
E
S
V
R
R
A
V
T
H
M
A
E
L
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04499
681
77135
D558
R
R
I
K
L
M
K
D
C
D
D
D
A
R
K
Honey Bee
Apis mellifera
XP_395275
528
60938
D405
R
R
M
K
Q
Y
K
D
K
G
E
D
P
K
K
Nematode Worm
Caenorhab. elegans
O45228
616
69804
V496
L
T
R
I
A
D
E
V
H
R
R
G
K
T
N
Sea Urchin
Strong. purpuratus
XP_782069
402
44953
S294
L
D
L
V
H
Q
R
S
S
S
S
V
N
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92983
499
54937
G392
L
M
E
K
A
S
N
G
S
G
F
G
V
V
L
Baker's Yeast
Sacchar. cerevisiae
P09368
476
53253
F369
I
N
G
E
D
S
Y
F
G
H
L
V
V
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
78.7
69.3
N.A.
69.7
69.2
N.A.
N.A.
N.A.
46.4
41
N.A.
28.3
28.5
26.9
26.4
Protein Similarity:
100
99.6
81.1
73.9
N.A.
75.5
75
N.A.
N.A.
N.A.
60
55.5
N.A.
45.6
46.8
43
43.4
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
26.6
26.6
N.A.
20
6.6
6.6
6.6
P-Site Similarity:
100
100
13.3
20
N.A.
13.3
13.3
N.A.
N.A.
N.A.
53.3
46.6
N.A.
33.3
20
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
21.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
22
8
0
8
0
0
29
0
8
8
0
% A
% Cys:
0
15
0
8
0
0
0
0
8
0
0
15
0
0
0
% C
% Asp:
8
8
0
8
8
8
0
15
0
8
8
15
0
0
0
% D
% Glu:
8
0
15
22
0
0
8
8
8
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% F
% Gly:
0
0
8
0
8
0
8
8
29
22
0
15
8
22
0
% G
% His:
0
0
0
0
8
8
0
15
29
8
0
0
36
0
0
% H
% Ile:
8
8
8
8
0
8
0
0
0
0
8
0
0
0
15
% I
% Lys:
8
0
0
22
0
0
15
0
8
0
0
0
8
8
22
% K
% Leu:
22
15
29
0
29
0
22
0
0
8
8
0
8
29
22
% L
% Met:
15
15
8
0
0
22
0
0
0
8
0
0
0
0
15
% M
% Asn:
0
8
0
0
0
0
22
0
8
0
0
0
8
8
8
% N
% Pro:
0
0
8
0
0
0
0
0
0
15
8
8
8
0
15
% P
% Gln:
0
0
0
0
8
8
0
8
0
0
8
0
0
0
0
% Q
% Arg:
29
15
22
15
8
0
15
0
0
8
15
22
0
8
0
% R
% Ser:
8
8
0
0
0
36
0
8
15
8
8
0
0
0
8
% S
% Thr:
0
8
0
0
0
0
0
22
0
0
0
0
0
8
0
% T
% Val:
0
0
8
8
15
0
8
8
0
22
0
15
15
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
8
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _