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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRODH2
All Species:
4.55
Human Site:
Y204
Identified Species:
7.69
UniProt:
Q9UF12
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UF12
NP_067055.1
536
58871
Y204
A
K
S
G
E
A
W
Y
E
G
N
L
G
A
M
Chimpanzee
Pan troglodytes
XP_524461
536
58825
Y204
A
K
S
G
E
A
W
Y
E
G
N
L
G
A
M
Rhesus Macaque
Macaca mulatta
XP_001112278
458
50173
E149
V
A
G
E
T
A
E
E
V
R
G
C
V
Q
Q
Dog
Lupus familis
XP_541686
567
62920
L201
A
M
D
S
G
Q
D
L
Q
I
S
C
L
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCZ9
456
50705
D147
D
L
S
R
A
L
V
D
A
H
G
P
A
R
N
Rat
Rattus norvegicus
Q2V057
456
50984
D147
D
L
S
R
A
V
A
D
A
H
G
P
A
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PAY6
466
52311
L156
E
Q
N
E
S
I
M
L
D
C
V
D
L
S
A
Zebra Danio
Brachydanio rerio
NP_001002391
465
52716
L156
S
N
N
P
M
M
Q
L
K
I
T
A
L
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04499
681
77135
E224
E
A
E
K
R
E
V
E
S
S
V
S
S
A
G
Honey Bee
Apis mellifera
XP_395275
528
60938
P194
V
L
T
H
H
A
K
P
D
D
F
M
K
K
F
Nematode Worm
Caenorhab. elegans
O45228
616
69804
S281
K
A
L
T
G
G
M
S
L
Q
E
G
R
L
T
Sea Urchin
Strong. purpuratus
XP_782069
402
44953
P92
E
V
A
R
P
N
Q
P
I
L
S
Q
L
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92983
499
54937
F190
K
S
L
P
T
S
H
F
S
S
V
V
V
K
I
Baker's Yeast
Sacchar. cerevisiae
P09368
476
53253
V167
V
K
E
T
I
S
S
V
H
N
I
L
L
P
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
78.7
69.3
N.A.
69.7
69.2
N.A.
N.A.
N.A.
46.4
41
N.A.
28.3
28.5
26.9
26.4
Protein Similarity:
100
99.6
81.1
73.9
N.A.
75.5
75
N.A.
N.A.
N.A.
60
55.5
N.A.
45.6
46.8
43
43.4
P-Site Identity:
100
100
6.6
6.6
N.A.
6.6
6.6
N.A.
N.A.
N.A.
0
0
N.A.
6.6
6.6
0
0
P-Site Similarity:
100
100
6.6
20
N.A.
6.6
6.6
N.A.
N.A.
N.A.
26.6
20
N.A.
6.6
26.6
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
21.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
22
8
0
15
29
8
0
15
0
0
8
15
22
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
15
0
0
0
% C
% Asp:
15
0
8
0
0
0
8
15
15
8
0
8
0
0
0
% D
% Glu:
22
0
15
15
15
8
8
15
15
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% F
% Gly:
0
0
8
15
15
8
0
0
0
15
22
8
15
0
8
% G
% His:
0
0
0
8
8
0
8
0
8
15
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
8
15
8
0
0
0
15
% I
% Lys:
15
22
0
8
0
0
8
0
8
0
0
0
8
15
0
% K
% Leu:
0
22
15
0
0
8
0
22
8
8
0
22
36
8
0
% L
% Met:
0
8
0
0
8
8
15
0
0
0
0
8
0
0
15
% M
% Asn:
0
8
15
0
0
8
0
0
0
8
15
0
0
8
22
% N
% Pro:
0
0
0
15
8
0
0
15
0
0
0
15
0
8
0
% P
% Gln:
0
8
0
0
0
8
15
0
8
8
0
8
0
8
8
% Q
% Arg:
0
0
0
22
8
0
0
0
0
8
0
0
8
22
0
% R
% Ser:
8
8
29
8
8
15
8
8
15
15
15
8
8
8
8
% S
% Thr:
0
0
8
15
15
0
0
0
0
0
8
0
0
0
8
% T
% Val:
22
8
0
0
0
8
15
8
8
0
22
8
15
8
0
% V
% Trp:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _