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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRODH2
All Species:
16.06
Human Site:
Y497
Identified Species:
27.18
UniProt:
Q9UF12
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UF12
NP_067055.1
536
58871
Y497
S
L
E
E
V
I
P
Y
L
I
R
R
A
Q
E
Chimpanzee
Pan troglodytes
XP_524461
536
58825
Y497
S
L
E
E
V
I
P
Y
L
I
R
R
A
Q
E
Rhesus Macaque
Macaca mulatta
XP_001112278
458
50173
R428
S
V
R
Q
A
T
K
R
M
W
E
L
G
I
P
Dog
Lupus familis
XP_541686
567
62920
Q493
H
V
A
G
T
W
P
Q
T
P
P
R
T
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCZ9
456
50705
A426
I
P
Y
L
I
R
R
A
Q
E
N
R
S
V
L
Rat
Rattus norvegicus
Q2V057
456
50984
A426
I
P
Y
L
I
R
R
A
Q
E
N
R
S
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6PAY6
466
52311
R435
S
V
L
P
Y
L
I
R
R
A
Q
E
N
Q
S
Zebra Danio
Brachydanio rerio
NP_001002391
465
52716
E435
E
R
D
L
L
R
Q
E
L
H
R
R
L
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04499
681
77135
Y635
P
V
E
E
V
L
P
Y
L
S
R
R
A
Q
E
Honey Bee
Apis mellifera
XP_395275
528
60938
Y482
P
V
K
E
V
L
P
Y
L
S
R
R
A
Q
E
Nematode Worm
Caenorhab. elegans
O45228
616
69804
Y573
P
V
E
E
V
L
P
Y
L
S
R
R
A
L
E
Sea Urchin
Strong. purpuratus
XP_782069
402
44953
R371
V
L
A
N
M
S
R
R
A
Q
E
N
K
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92983
499
54937
A469
I
P
Y
L
L
R
R
A
Y
E
N
R
G
M
M
Baker's Yeast
Sacchar. cerevisiae
P09368
476
53253
R446
T
K
D
Y
L
L
R
R
L
Q
E
N
G
D
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
78.7
69.3
N.A.
69.7
69.2
N.A.
N.A.
N.A.
46.4
41
N.A.
28.3
28.5
26.9
26.4
Protein Similarity:
100
99.6
81.1
73.9
N.A.
75.5
75
N.A.
N.A.
N.A.
60
55.5
N.A.
45.6
46.8
43
43.4
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
13.3
26.6
N.A.
73.3
66.6
66.6
6.6
P-Site Similarity:
100
100
26.6
26.6
N.A.
20
20
N.A.
N.A.
N.A.
33.3
46.6
N.A.
86.6
86.6
80
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.9
21.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
38.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
8
0
0
22
8
8
0
0
36
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
8
0
29
36
0
0
0
8
0
22
22
8
0
0
43
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
22
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
22
0
0
0
15
15
8
0
0
15
0
0
0
8
0
% I
% Lys:
0
8
8
0
0
0
8
0
0
0
0
0
8
8
0
% K
% Leu:
0
22
8
29
22
36
0
0
50
0
0
8
8
8
15
% L
% Met:
0
0
0
0
8
0
0
0
8
0
0
0
0
8
8
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
22
15
8
0
0
% N
% Pro:
22
22
0
8
0
0
43
0
0
8
8
0
0
0
8
% P
% Gln:
0
0
0
8
0
0
8
8
15
15
8
0
0
36
0
% Q
% Arg:
0
8
8
0
0
29
36
29
8
0
43
72
0
8
8
% R
% Ser:
29
0
0
0
0
8
0
0
0
22
0
0
15
0
8
% S
% Thr:
8
0
0
0
8
8
0
0
8
0
0
0
8
8
0
% T
% Val:
8
43
0
0
36
0
0
0
0
0
0
0
0
15
8
% V
% Trp:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
22
8
8
0
0
36
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _