Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNOT8 All Species: 33.33
Human Site: S172 Identified Species: 52.38
UniProt: Q9UFF9 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UFF9 NP_004770.4 292 33540 S172 M V K L L T D S R L P E E E H
Chimpanzee Pan troglodytes XP_518053 343 38684 S223 M V K L L T D S R L P E E E H
Rhesus Macaque Macaca mulatta XP_001112600 254 29154 I154 L N L F F P S I Y D V K Y L M
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9D8X5 292 33556 S172 M V K L L T D S R L P E E E H
Rat Rattus norvegicus NP_001008383 292 33528 S172 M V K L L T D S R L P E E E H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508901 285 32701 S172 L I K I L T N S N L P E E E L
Chicken Gallus gallus NP_001025789 292 33434 S172 M V K L L T D S R L P E E E H
Frog Xenopus laevis Q3KQ85 285 32745 S172 L I K I L T N S N L P E V E Q
Zebra Danio Brachydanio rerio Q08BM8 286 32858 S172 L I K I L S N S K L P D E E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_729775 293 33460 Q181 L L K L L T D Q N L P P D E S
Honey Bee Apis mellifera XP_623444 302 34140 Q189 L L K L L T D Q N L P Q E E S
Nematode Worm Caenorhab. elegans Q17345 310 33820 G183 L L K S I T L G D L P K E E S
Sea Urchin Strong. purpuratus XP_786386 284 32557 T170 L I K L M T A T N L P S E E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SAI2 274 31182 K172 Y D F G Y L L K L L T C Q N L
Baker's Yeast Sacchar. cerevisiae P39008 433 49664 D321 L I N I L M N D S M P N N K E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.8 86.9 N.A. N.A. 99.3 99.3 N.A. 75 97.5 73.2 74.3 N.A. 64.5 66.2 43.5 60.9
Protein Similarity: 100 81.3 86.9 N.A. N.A. 99.6 99.6 N.A. 86.6 98.9 86.3 87.3 N.A. 80.8 77.8 60.9 76.3
P-Site Identity: 100 100 0 N.A. N.A. 100 100 N.A. 60 100 53.3 46.6 N.A. 53.3 60 40 46.6
P-Site Similarity: 100 100 13.3 N.A. N.A. 100 100 N.A. 86.6 100 80 93.3 N.A. 73.3 80 66.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. 50 24.9 N.A.
Protein Similarity: N.A. N.A. N.A. 70.8 40.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 7 0 0 0 0 47 7 7 7 0 7 7 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 47 67 80 7 % E
% Phe: 0 0 7 7 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 % H
% Ile: 0 34 0 27 7 0 0 7 0 0 0 0 0 0 0 % I
% Lys: 0 0 80 0 0 0 0 7 7 0 0 14 0 7 0 % K
% Leu: 60 20 7 54 74 7 14 0 7 87 0 0 0 7 14 % L
% Met: 34 0 0 0 7 7 0 0 0 7 0 0 0 0 7 % M
% Asn: 0 7 7 0 0 0 27 0 34 0 0 7 7 7 0 % N
% Pro: 0 0 0 0 0 7 0 0 0 0 87 7 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 14 0 0 0 7 7 0 7 % Q
% Arg: 0 0 0 0 0 0 0 0 34 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 0 7 7 54 7 0 0 7 0 0 27 % S
% Thr: 0 0 0 0 0 74 0 7 0 0 7 0 0 0 0 % T
% Val: 0 34 0 0 0 0 0 0 0 0 7 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 7 0 0 0 7 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _