KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CNOT8
All Species:
20.91
Human Site:
S249
Identified Species:
32.86
UniProt:
Q9UFF9
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UFF9
NP_004770.4
292
33540
S249
K
E
L
F
F
E
D
S
I
D
D
A
K
Y
C
Chimpanzee
Pan troglodytes
XP_518053
343
38684
S300
K
E
L
F
F
E
D
S
I
D
D
A
K
Y
C
Rhesus Macaque
Macaca mulatta
XP_001112600
254
29154
D214
F
F
E
D
S
I
D
D
A
K
Y
C
G
R
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8X5
292
33556
S249
K
E
L
F
F
E
D
S
I
D
D
A
K
Y
C
Rat
Rattus norvegicus
NP_001008383
292
33528
S249
K
E
L
F
F
E
D
S
I
D
D
A
K
Y
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508901
285
32701
F245
F
F
K
M
R
E
M
F
F
E
D
H
I
D
D
Chicken
Gallus gallus
NP_001025789
292
33434
T249
K
E
L
F
F
E
D
T
I
D
D
A
K
Y
C
Frog
Xenopus laevis
Q3KQ85
285
32745
F245
F
F
K
M
R
E
M
F
F
E
D
H
I
D
D
Zebra Danio
Brachydanio rerio
Q08BM8
286
32858
F245
F
F
K
M
R
E
M
F
F
E
D
H
I
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729775
293
33460
R251
G
M
A
F
F
K
M
R
E
M
F
F
E
D
N
Honey Bee
Apis mellifera
XP_623444
302
34140
F262
F
F
K
M
R
E
M
F
F
E
D
N
I
D
D
Nematode Worm
Caenorhab. elegans
Q17345
310
33820
N264
K
K
Q
F
F
G
D
N
W
N
Q
I
A
P
L
Sea Urchin
Strong. purpuratus
XP_786386
284
32557
Y243
F
L
K
M
R
E
C
Y
F
E
D
N
I
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SAI2
274
31182
S234
G
I
C
H
Q
A
G
S
D
S
L
L
T
S
C
Baker's Yeast
Sacchar. cerevisiae
P39008
433
49664
T391
R
F
S
I
F
T
T
T
G
G
Q
S
L
L
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
86.9
N.A.
N.A.
99.3
99.3
N.A.
75
97.5
73.2
74.3
N.A.
64.5
66.2
43.5
60.9
Protein Similarity:
100
81.3
86.9
N.A.
N.A.
99.6
99.6
N.A.
86.6
98.9
86.3
87.3
N.A.
80.8
77.8
60.9
76.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
100
100
N.A.
13.3
93.3
13.3
13.3
N.A.
13.3
13.3
26.6
13.3
P-Site Similarity:
100
100
6.6
N.A.
N.A.
100
100
N.A.
20
100
20
20
N.A.
26.6
20
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
50
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.8
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
0
7
0
0
34
7
0
0
% A
% Cys:
0
0
7
0
0
0
7
0
0
0
0
7
0
0
40
% C
% Asp:
0
0
0
7
0
0
47
7
7
34
67
0
0
40
34
% D
% Glu:
0
34
7
0
0
67
0
0
7
34
0
0
7
0
0
% E
% Phe:
40
40
0
47
54
0
0
27
34
0
7
7
0
0
0
% F
% Gly:
14
0
0
0
0
7
7
0
7
7
0
0
7
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
20
0
0
0
% H
% Ile:
0
7
0
7
0
7
0
0
34
0
0
7
34
0
0
% I
% Lys:
40
7
34
0
0
7
0
0
0
7
0
0
34
0
0
% K
% Leu:
0
7
34
0
0
0
0
0
0
0
7
7
7
7
14
% L
% Met:
0
7
0
34
0
0
34
0
0
7
0
0
0
0
7
% M
% Asn:
0
0
0
0
0
0
0
7
0
7
0
14
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% P
% Gln:
0
0
7
0
7
0
0
0
0
0
14
0
0
0
0
% Q
% Arg:
7
0
0
0
34
0
0
7
0
0
0
0
0
7
0
% R
% Ser:
0
0
7
0
7
0
0
34
0
7
0
7
0
7
0
% S
% Thr:
0
0
0
0
0
7
7
14
0
0
0
0
7
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
7
0
0
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _