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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PISD
All Species:
36.67
Human Site:
S166
Identified Species:
67.22
UniProt:
Q9UG56
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UG56
NP_055153.1
408
46573
S166
L
H
H
Y
R
N
L
S
E
F
F
R
R
K
L
Chimpanzee
Pan troglodytes
XP_515087
419
47798
S176
L
H
H
Y
R
N
L
S
E
F
F
R
R
K
L
Rhesus Macaque
Macaca mulatta
XP_001111773
409
46891
S166
L
H
H
Y
R
N
L
S
E
F
F
R
R
K
L
Dog
Lupus familis
XP_534739
409
46776
S166
L
H
H
Y
R
N
L
S
E
F
F
R
R
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSF4
406
45908
S163
L
H
H
Y
R
N
L
S
E
F
F
R
R
K
L
Rat
Rattus norvegicus
XP_002725046
409
45994
S166
L
Q
H
Y
R
N
L
S
E
F
F
R
R
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515601
373
42661
S149
R
P
V
C
G
V
H
S
V
I
S
P
S
D
G
Chicken
Gallus gallus
XP_415253
409
46521
S166
L
H
H
Y
R
N
L
S
E
F
F
R
R
K
L
Frog
Xenopus laevis
NP_001087912
411
47318
S173
L
H
Q
Y
R
N
L
S
E
F
F
R
R
K
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651208
447
50470
A195
Y
E
H
Y
N
S
L
A
E
F
F
T
R
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10949
377
42469
P148
R
M
D
D
C
V
D
P
D
F
K
N
Y
P
S
Sea Urchin
Strong. purpuratus
XP_001180823
382
43384
S151
D
A
H
H
M
L
V
S
P
C
D
G
R
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39006
500
56576
S184
L
T
H
Y
A
N
L
S
E
F
F
Y
R
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.3
96.8
91.1
N.A.
84.5
84.5
N.A.
73
79.2
64.2
N.A.
N.A.
39.3
N.A.
34
48.7
Protein Similarity:
100
78.5
97.3
94.1
N.A.
89.2
89.2
N.A.
79.1
86.3
72.9
N.A.
N.A.
52.7
N.A.
50.7
60.5
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
6.6
100
93.3
N.A.
N.A.
53.3
N.A.
6.6
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
6.6
100
93.3
N.A.
N.A.
66.6
N.A.
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
8
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
0
8
0
8
0
8
0
0
8
0
% D
% Glu:
0
8
0
0
0
0
0
0
77
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
85
77
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
8
% G
% His:
0
54
77
8
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
0
62
0
% K
% Leu:
70
0
0
0
0
8
77
0
0
0
0
0
0
0
77
% L
% Met:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
70
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
8
8
0
0
8
0
16
0
% P
% Gln:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
16
0
0
0
62
0
0
0
0
0
0
62
85
0
0
% R
% Ser:
0
0
0
0
0
8
0
85
0
0
8
0
8
0
8
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
8
0
0
16
8
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
77
0
0
0
0
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _