Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PISD All Species: 35.45
Human Site: S352 Identified Species: 65
UniProt: Q9UG56 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UG56 NP_055153.1 408 46573 S352 K G S Y N D F S F V T H T N R
Chimpanzee Pan troglodytes XP_515087 419 47798 S363 K G S Y N D F S F V T H T N R
Rhesus Macaque Macaca mulatta XP_001111773 409 46891 S353 K G S Y N D F S F V T H T N R
Dog Lupus familis XP_534739 409 46776 S353 K G S Y N D F S F V T H A N K
Cat Felis silvestris
Mouse Mus musculus Q8BSF4 406 45908 S350 K G S Y N D L S F V T H A N K
Rat Rattus norvegicus XP_002725046 409 45994 S353 K G S Y N D L S F V T H A N K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515601 373 42661 S317 K G S Y N D F S F I T N N N K
Chicken Gallus gallus XP_415253 409 46521 S353 K G S Y N D F S F I S N N N K
Frog Xenopus laevis NP_001087912 411 47318 S355 K G S Y N D L S Y I T N N N Q
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651208 447 50470 S379 N V G K H P P S T Y E Y D E L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10949 377 42469 E324 T Q K I M N T E T E I H A P Y
Sea Urchin Strong. purpuratus XP_001180823 382 43384 K320 K P G V Y Y D K S L K S C R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39006 500 56576 Y434 H L E P H T C Y Q A V Y E N A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.3 96.8 91.1 N.A. 84.5 84.5 N.A. 73 79.2 64.2 N.A. N.A. 39.3 N.A. 34 48.7
Protein Similarity: 100 78.5 97.3 94.1 N.A. 89.2 89.2 N.A. 79.1 86.3 72.9 N.A. N.A. 52.7 N.A. 50.7 60.5
P-Site Identity: 100 100 100 86.6 N.A. 80 80 N.A. 73.3 66.6 60 N.A. N.A. 6.6 N.A. 6.6 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 93.3 93.3 86.6 N.A. N.A. 20 N.A. 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 8 0 0 31 0 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 70 8 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 8 0 0 0 0 8 0 8 8 0 8 8 0 % E
% Phe: 0 0 0 0 0 0 47 0 62 0 0 0 0 0 0 % F
% Gly: 0 70 16 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 16 0 0 0 0 0 0 54 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 24 8 0 0 0 0 % I
% Lys: 77 0 8 8 0 0 0 8 0 0 8 0 0 0 47 % K
% Leu: 0 8 0 0 0 0 24 0 0 8 0 0 0 0 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 70 8 0 0 0 0 0 24 24 77 0 % N
% Pro: 0 8 0 8 0 8 8 0 0 0 0 0 0 8 0 % P
% Gln: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 24 % R
% Ser: 0 0 70 0 0 0 0 77 8 0 8 8 0 0 0 % S
% Thr: 8 0 0 0 0 8 8 0 16 0 62 0 24 0 0 % T
% Val: 0 8 0 8 0 0 0 0 0 47 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 70 8 8 0 8 8 8 0 16 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _