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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PISD
All Species:
32.42
Human Site:
Y111
Identified Species:
59.44
UniProt:
Q9UG56
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UG56
NP_055153.1
408
46573
Y111
G
H
W
E
V
A
L
Y
K
S
V
P
T
R
L
Chimpanzee
Pan troglodytes
XP_515087
419
47798
Y121
P
V
S
R
V
A
L
Y
K
S
V
P
T
R
L
Rhesus Macaque
Macaca mulatta
XP_001111773
409
46891
Y111
G
H
W
E
V
A
L
Y
K
S
V
P
T
R
L
Dog
Lupus familis
XP_534739
409
46776
Y111
G
H
W
E
V
A
L
Y
K
S
V
P
T
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSF4
406
45908
Y108
S
H
W
E
V
S
L
Y
K
S
V
P
T
R
L
Rat
Rattus norvegicus
XP_002725046
409
45994
Y111
S
H
W
E
V
S
L
Y
K
S
V
P
T
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515601
373
42661
R100
V
E
L
P
N
W
L
R
K
P
V
Y
S
L
Y
Chicken
Gallus gallus
XP_415253
409
46521
Y111
S
E
W
E
V
A
L
Y
K
S
V
P
T
R
L
Frog
Xenopus laevis
NP_001087912
411
47318
Y118
P
T
S
R
V
A
L
Y
K
T
V
P
T
R
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651208
447
50470
Y140
S
E
L
Q
S
R
I
Y
C
S
L
P
L
R
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10949
377
42469
I99
H
Y
Y
S
N
W
K
I
R
V
Y
L
S
L
P
Sea Urchin
Strong. purpuratus
XP_001180823
382
43384
M102
P
L
F
L
R
A
P
M
Y
S
L
Y
V
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39006
500
56576
Y129
N
N
W
L
F
F
C
Y
S
T
L
P
L
N
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.3
96.8
91.1
N.A.
84.5
84.5
N.A.
73
79.2
64.2
N.A.
N.A.
39.3
N.A.
34
48.7
Protein Similarity:
100
78.5
97.3
94.1
N.A.
89.2
89.2
N.A.
79.1
86.3
72.9
N.A.
N.A.
52.7
N.A.
50.7
60.5
P-Site Identity:
100
73.3
100
100
N.A.
86.6
86.6
N.A.
20
86.6
66.6
N.A.
N.A.
26.6
N.A.
0
26.6
P-Site Similarity:
100
73.3
100
100
N.A.
93.3
93.3
N.A.
26.6
86.6
73.3
N.A.
N.A.
53.3
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
54
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
24
0
47
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
39
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
8
0
70
0
0
0
0
0
0
% K
% Leu:
0
8
16
16
0
0
70
0
0
0
24
8
16
16
70
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
16
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
24
0
0
8
0
0
8
0
0
8
0
77
0
0
8
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
16
8
8
0
8
8
0
0
0
0
77
0
% R
% Ser:
31
0
16
8
8
16
0
0
8
70
0
0
16
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
16
0
0
62
0
0
% T
% Val:
8
8
0
0
62
0
0
0
0
8
70
0
8
0
0
% V
% Trp:
0
0
54
0
0
16
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
0
77
8
0
8
16
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _