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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PISD
All Species:
35.15
Human Site:
Y348
Identified Species:
64.44
UniProt:
Q9UG56
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UG56
NP_055153.1
408
46573
Y348
P
R
H
S
K
G
S
Y
N
D
F
S
F
V
T
Chimpanzee
Pan troglodytes
XP_515087
419
47798
Y359
P
R
H
S
K
G
S
Y
N
D
F
S
F
V
T
Rhesus Macaque
Macaca mulatta
XP_001111773
409
46891
Y349
P
R
H
S
K
G
S
Y
N
D
F
S
F
V
T
Dog
Lupus familis
XP_534739
409
46776
Y349
P
R
Y
S
K
G
S
Y
N
D
F
S
F
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSF4
406
45908
Y346
P
R
Y
S
K
G
S
Y
N
D
L
S
F
V
T
Rat
Rattus norvegicus
XP_002725046
409
45994
Y349
P
S
Y
S
K
G
S
Y
N
D
L
S
F
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515601
373
42661
Y313
P
R
Y
S
K
G
S
Y
N
D
F
S
F
I
T
Chicken
Gallus gallus
XP_415253
409
46521
Y349
P
R
Y
S
K
G
S
Y
N
D
F
S
F
I
S
Frog
Xenopus laevis
NP_001087912
411
47318
Y351
P
R
Y
S
K
G
S
Y
N
D
L
S
Y
I
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651208
447
50470
K375
W
T
G
F
N
V
G
K
H
P
P
S
T
Y
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10949
377
42469
I320
V
R
R
K
T
Q
K
I
M
N
T
E
T
E
I
Sea Urchin
Strong. purpuratus
XP_001180823
382
43384
V316
T
G
K
C
K
P
G
V
Y
Y
D
K
S
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39006
500
56576
P430
K
S
D
K
H
L
E
P
H
T
C
Y
Q
A
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.3
96.8
91.1
N.A.
84.5
84.5
N.A.
73
79.2
64.2
N.A.
N.A.
39.3
N.A.
34
48.7
Protein Similarity:
100
78.5
97.3
94.1
N.A.
89.2
89.2
N.A.
79.1
86.3
72.9
N.A.
N.A.
52.7
N.A.
50.7
60.5
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
86.6
80
73.3
N.A.
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
100
100
93.3
N.A.
N.A.
13.3
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
70
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
0
0
0
8
0
8
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
47
0
62
0
0
% F
% Gly:
0
8
8
0
0
70
16
0
0
0
0
0
0
0
0
% G
% His:
0
0
24
0
8
0
0
0
16
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
24
8
% I
% Lys:
8
0
8
16
77
0
8
8
0
0
0
8
0
0
8
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
24
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
70
8
0
0
0
0
0
% N
% Pro:
70
0
0
0
0
8
0
8
0
8
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
70
8
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
0
70
0
0
70
0
0
0
0
77
8
0
8
% S
% Thr:
8
8
0
0
8
0
0
0
0
8
8
0
16
0
62
% T
% Val:
8
0
0
0
0
8
0
8
0
0
0
0
0
47
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
47
0
0
0
0
70
8
8
0
8
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _