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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERGEF
All Species:
13.03
Human Site:
S124
Identified Species:
28.67
UniProt:
Q9UGK8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGK8
NP_036271.1
458
48981
S124
T
E
N
G
Q
V
L
S
C
G
S
N
S
F
G
Chimpanzee
Pan troglodytes
XP_521852
885
98391
S551
T
E
N
G
Q
V
L
S
C
G
S
N
S
F
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q80YD6
464
49207
S124
T
E
K
G
Q
V
L
S
C
G
S
N
A
F
G
Rat
Rattus norvegicus
XP_344892
450
47572
S124
T
E
K
G
Q
V
L
S
C
G
S
N
A
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421009
341
35614
E52
A
V
I
T
G
A
G
E
L
F
V
C
G
H
N
Frog
Xenopus laevis
NP_001088703
394
41469
W105
V
S
K
V
A
C
G
W
D
F
T
L
I
L
T
Zebra Danio
Brachydanio rerio
XP_694032
448
47864
V119
S
D
S
G
E
L
L
V
C
G
Q
N
H
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608602
378
41496
F89
K
M
I
P
T
E
Y
F
G
D
V
P
V
E
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781445
280
30061
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141147
443
47140
F107
H
G
N
S
S
D
V
F
T
P
Q
P
V
K
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P31386
333
36463
G44
I
V
R
K
I
A
C
G
G
N
H
S
V
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.1
N.A.
N.A.
N.A.
72.1
73.5
N.A.
N.A.
46.9
43.8
46
N.A.
26.2
N.A.
N.A.
26.4
Protein Similarity:
100
50.7
N.A.
N.A.
N.A.
81
81.2
N.A.
N.A.
56.9
59.8
61.5
N.A.
40.6
N.A.
N.A.
37.5
P-Site Identity:
100
100
N.A.
N.A.
N.A.
86.6
86.6
N.A.
N.A.
0
0
40
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
93.3
93.3
N.A.
N.A.
0
6.6
73.3
N.A.
0
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
28.3
N.A.
N.A.
24.4
N.A.
Protein Similarity:
N.A.
44.3
N.A.
N.A.
37.5
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
19
0
0
0
0
0
0
19
0
10
% A
% Cys:
0
0
0
0
0
10
10
0
46
0
0
10
0
0
0
% C
% Asp:
0
10
0
0
0
10
0
0
10
10
0
0
0
0
0
% D
% Glu:
0
37
0
0
10
10
0
10
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
19
0
19
0
0
0
37
0
% F
% Gly:
0
10
0
46
10
0
19
10
19
46
0
0
10
0
46
% G
% His:
10
0
0
0
0
0
0
0
0
0
10
0
10
10
0
% H
% Ile:
10
0
19
0
10
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
10
0
28
10
0
0
0
0
0
0
0
0
0
19
0
% K
% Leu:
0
0
0
0
0
10
46
0
10
0
0
10
0
10
10
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
28
0
0
0
0
0
0
10
0
46
0
0
10
% N
% Pro:
0
0
0
10
0
0
0
0
0
10
0
19
0
0
0
% P
% Gln:
0
0
0
0
37
0
0
0
0
0
19
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
10
10
10
0
0
37
0
0
37
10
19
0
0
% S
% Thr:
37
0
0
10
10
0
0
0
10
0
10
0
0
0
19
% T
% Val:
10
19
0
10
0
37
10
10
0
0
19
0
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _