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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERGEF
All Species:
13.03
Human Site:
S226
Identified Species:
28.67
UniProt:
Q9UGK8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGK8
NP_036271.1
458
48981
S226
A
G
S
D
H
S
A
S
L
T
D
A
G
E
V
Chimpanzee
Pan troglodytes
XP_521852
885
98391
S653
A
G
S
D
H
S
A
S
L
T
D
A
G
E
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q80YD6
464
49207
S226
A
G
S
D
H
S
A
S
L
T
D
T
G
E
L
Rat
Rattus norvegicus
XP_344892
450
47572
S226
A
G
S
D
H
S
A
S
L
T
D
T
G
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421009
341
35614
Q129
S
G
P
C
L
I
P
Q
K
I
K
Q
S
L
K
Frog
Xenopus laevis
NP_001088703
394
41469
F182
L
A
S
H
A
R
R
F
S
Q
Q
K
P
I
P
Zebra Danio
Brachydanio rerio
XP_694032
448
47864
A214
A
G
L
R
H
A
L
A
S
T
A
S
G
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608602
378
41496
K166
A
V
L
T
Q
D
N
K
I
Y
V
F
G
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781445
280
30061
R67
S
D
I
N
K
L
V
R
V
P
D
L
R
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141147
443
47140
A184
A
G
A
E
H
T
A
A
V
T
E
D
G
D
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P31386
333
36463
Q121
G
C
Y
E
F
T
Q
Q
H
V
P
L
N
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.1
N.A.
N.A.
N.A.
72.1
73.5
N.A.
N.A.
46.9
43.8
46
N.A.
26.2
N.A.
N.A.
26.4
Protein Similarity:
100
50.7
N.A.
N.A.
N.A.
81
81.2
N.A.
N.A.
56.9
59.8
61.5
N.A.
40.6
N.A.
N.A.
37.5
P-Site Identity:
100
100
N.A.
N.A.
N.A.
86.6
86.6
N.A.
N.A.
6.6
6.6
40
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
93.3
93.3
N.A.
N.A.
13.3
6.6
60
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
28.3
N.A.
N.A.
24.4
N.A.
Protein Similarity:
N.A.
44.3
N.A.
N.A.
37.5
N.A.
P-Site Identity:
N.A.
40
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
64
10
10
0
10
10
46
19
0
0
10
19
0
0
0
% A
% Cys:
0
10
0
10
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
10
0
37
0
10
0
0
0
0
46
10
0
10
0
% D
% Glu:
0
0
0
19
0
0
0
0
0
0
10
0
0
37
0
% E
% Phe:
0
0
0
0
10
0
0
10
0
0
0
10
0
0
0
% F
% Gly:
10
64
0
0
0
0
0
0
0
0
0
0
64
0
0
% G
% His:
0
0
0
10
55
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
10
10
0
0
0
10
0
% I
% Lys:
0
0
0
0
10
0
0
10
10
0
10
10
0
0
10
% K
% Leu:
10
0
19
0
10
10
10
0
37
0
0
19
0
10
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
10
0
0
0
0
0
10
0
10
% N
% Pro:
0
0
10
0
0
0
10
0
0
10
10
0
10
10
10
% P
% Gln:
0
0
0
0
10
0
10
19
0
10
10
10
0
0
0
% Q
% Arg:
0
0
0
10
0
10
10
10
0
0
0
0
10
10
0
% R
% Ser:
19
0
46
0
0
37
0
37
19
0
0
10
10
10
0
% S
% Thr:
0
0
0
10
0
19
0
0
0
55
0
19
0
0
0
% T
% Val:
0
10
0
0
0
0
10
0
19
10
10
0
0
0
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _