KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SERGEF
All Species:
4.24
Human Site:
S418
Identified Species:
9.33
UniProt:
Q9UGK8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGK8
NP_036271.1
458
48981
S418
D
P
K
V
T
Y
L
S
P
D
A
I
E
D
T
Chimpanzee
Pan troglodytes
XP_521852
885
98391
S845
D
S
R
V
T
Y
L
S
P
D
A
I
E
D
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q80YD6
464
49207
L420
D
L
K
V
T
C
P
L
P
D
D
T
E
N
T
Rat
Rattus norvegicus
XP_344892
450
47572
P407
L
C
Q
L
P
A
H
P
A
P
C
Q
D
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421009
341
35614
H302
D
G
T
E
A
N
V
H
V
P
K
P
V
K
A
Frog
Xenopus laevis
NP_001088703
394
41469
G355
W
N
E
H
G
M
C
G
N
G
S
E
T
N
V
Zebra Danio
Brachydanio rerio
XP_694032
448
47864
W396
G
R
V
F
S
W
G
W
N
E
H
G
M
C
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608602
378
41496
G339
T
W
G
W
N
E
H
G
N
C
G
N
N
S
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781445
280
30061
G241
A
W
G
W
N
E
H
G
M
C
A
D
G
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141147
443
47140
A394
S
S
T
A
A
P
F
A
A
K
V
W
V
S
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P31386
333
36463
W294
Y
N
V
Y
C
W
G
W
G
E
H
G
N
C
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.1
N.A.
N.A.
N.A.
72.1
73.5
N.A.
N.A.
46.9
43.8
46
N.A.
26.2
N.A.
N.A.
26.4
Protein Similarity:
100
50.7
N.A.
N.A.
N.A.
81
81.2
N.A.
N.A.
56.9
59.8
61.5
N.A.
40.6
N.A.
N.A.
37.5
P-Site Identity:
100
86.6
N.A.
N.A.
N.A.
53.3
6.6
N.A.
N.A.
6.6
0
0
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
N.A.
N.A.
N.A.
60
26.6
N.A.
N.A.
13.3
20
20
N.A.
6.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
28.3
N.A.
N.A.
24.4
N.A.
Protein Similarity:
N.A.
44.3
N.A.
N.A.
37.5
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
19
10
0
10
19
0
28
0
0
0
10
% A
% Cys:
0
10
0
0
10
10
10
0
0
19
10
0
0
19
0
% C
% Asp:
37
0
0
0
0
0
0
0
0
28
10
10
10
19
0
% D
% Glu:
0
0
10
10
0
19
0
0
0
19
0
10
28
0
0
% E
% Phe:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
19
0
10
0
19
28
10
10
10
19
10
0
19
% G
% His:
0
0
0
10
0
0
28
10
0
0
19
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% I
% Lys:
0
0
19
0
0
0
0
0
0
10
10
0
0
10
10
% K
% Leu:
10
10
0
10
0
0
19
10
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
10
0
0
% M
% Asn:
0
19
0
0
19
10
0
0
28
0
0
10
19
19
0
% N
% Pro:
0
10
0
0
10
10
10
10
28
19
0
10
0
0
10
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
19
0
0
10
0
0
19
0
0
10
0
0
19
0
% S
% Thr:
10
0
19
0
28
0
0
0
0
0
0
10
10
10
46
% T
% Val:
0
0
19
28
0
0
10
0
10
0
10
0
19
0
10
% V
% Trp:
10
19
0
19
0
19
0
19
0
0
0
10
0
0
0
% W
% Tyr:
10
0
0
10
0
19
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _