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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHRNA9 All Species: 15.15
Human Site: S357 Identified Species: 27.78
UniProt: Q9UGM1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UGM1 NP_060051.2 479 54780 S357 F V Y D V G E S C L S P H H S
Chimpanzee Pan troglodytes Q5IS76 494 56903 K361 L M R W P L D K T R G T G S D
Rhesus Macaque Macaca mulatta Q866A2 502 56411 S372 S L A S V E M S A V A P P P A
Dog Lupus familis XP_545950 701 79638 S579 C V Y D V G E S C L S A H H D
Cat Felis silvestris
Mouse Mus musculus Q9R0W9 494 56789 P371 E A G G V K D P K S H T K R P
Rat Rattus norvegicus P43144 479 54507 S357 F V Y D V G E S C L S P R H S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508727 582 66030 S463 L V Y K V G E S C T S P Q R G
Chicken Gallus gallus Q9PTS8 484 55267 N359 F V Y D V G E N C T S P R R E
Frog Xenopus laevis P05377 457 52088 F346 T I P N I M F F S T M K R P S
Zebra Danio Brachydanio rerio XP_001920894 457 51985 S344 E N C T T P E S D R G P F F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P09478 567 64001 E370 P E E D Q P P E V L T D V Y H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23022 511 59436 D378 F M R R P I D D Y E E K F D D
Sea Urchin Strong. purpuratus XP_786790 570 65253 Y406 Y M K R P K R Y N H G E N P N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34.4 35.6 65.3 N.A. 35 91 N.A. 62.2 73.1 35.2 64.9 N.A. 34.2 N.A. 32 34.7
Protein Similarity: 100 57 55.9 66.4 N.A. 57.8 95.8 N.A. 71.4 84.9 57.4 79.1 N.A. 52.3 N.A. 52 52.9
P-Site Identity: 100 0 20 80 N.A. 6.6 93.3 N.A. 60 66.6 6.6 26.6 N.A. 13.3 N.A. 6.6 0
P-Site Similarity: 100 13.3 46.6 80 N.A. 13.3 93.3 N.A. 60 73.3 26.6 26.6 N.A. 26.6 N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 0 0 8 0 8 8 0 0 8 % A
% Cys: 8 0 8 0 0 0 0 0 39 0 0 0 0 0 0 % C
% Asp: 0 0 0 39 0 0 24 8 8 0 0 8 0 8 24 % D
% Glu: 16 8 8 0 0 8 47 8 0 8 8 8 0 0 8 % E
% Phe: 31 0 0 0 0 0 8 8 0 0 0 0 16 8 0 % F
% Gly: 0 0 8 8 0 39 0 0 0 0 24 0 8 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 8 8 0 16 24 8 % H
% Ile: 0 8 0 0 8 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 8 0 16 0 8 8 0 0 16 8 0 0 % K
% Leu: 16 8 0 0 0 8 0 0 0 31 0 0 0 0 0 % L
% Met: 0 24 0 0 0 8 8 0 0 0 8 0 0 0 0 % M
% Asn: 0 8 0 8 0 0 0 8 8 0 0 0 8 0 8 % N
% Pro: 8 0 8 0 24 16 8 8 0 0 0 47 8 24 8 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 0 0 16 16 0 0 8 0 0 16 0 0 24 24 0 % R
% Ser: 8 0 0 8 0 0 0 47 8 8 39 0 0 8 31 % S
% Thr: 8 0 0 8 8 0 0 0 8 24 8 16 0 0 0 % T
% Val: 0 39 0 0 54 0 0 0 8 8 0 0 8 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 39 0 0 0 0 8 8 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _