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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHRNA9
All Species:
14.24
Human Site:
S446
Identified Species:
26.11
UniProt:
Q9UGM1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGM1
NP_060051.2
479
54780
S446
K
A
T
S
S
K
G
S
E
W
K
K
V
A
K
Chimpanzee
Pan troglodytes
Q5IS76
494
56903
D454
N
E
T
K
E
V
E
D
D
W
K
Y
V
A
M
Rhesus Macaque
Macaca mulatta
Q866A2
502
56411
K461
E
A
V
C
S
E
W
K
F
A
A
C
V
V
D
Dog
Lupus familis
XP_545950
701
79638
S668
K
A
T
N
S
K
G
S
E
W
K
K
V
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0W9
494
56789
D454
N
E
T
N
E
V
E
D
D
W
K
Y
M
A
M
Rat
Rattus norvegicus
P43144
479
54507
S446
K
A
T
N
S
K
G
S
E
W
K
K
V
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508727
582
66030
S421
R
S
H
S
A
K
G
S
E
W
K
K
V
A
R
Chicken
Gallus gallus
Q9PTS8
484
55267
I451
K
A
N
R
A
K
G
I
E
W
K
K
V
A
K
Frog
Xenopus laevis
P05377
457
52088
L426
W
K
F
V
A
M
V
L
D
H
I
L
L
A
V
Zebra Danio
Brachydanio rerio
XP_001920894
457
51985
A424
R
G
H
Q
A
K
G
A
E
W
K
K
V
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09478
567
64001
E502
D
K
F
E
S
V
E
E
D
W
K
Y
V
A
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23022
511
59436
Y457
K
I
D
E
D
W
K
Y
V
A
M
V
L
D
R
Sea Urchin
Strong. purpuratus
XP_786790
570
65253
E504
D
E
F
N
S
V
T
E
D
W
K
Y
V
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.4
35.6
65.3
N.A.
35
91
N.A.
62.2
73.1
35.2
64.9
N.A.
34.2
N.A.
32
34.7
Protein Similarity:
100
57
55.9
66.4
N.A.
57.8
95.8
N.A.
71.4
84.9
57.4
79.1
N.A.
52.3
N.A.
52
52.9
P-Site Identity:
100
33.3
20
93.3
N.A.
26.6
93.3
N.A.
66.6
73.3
6.6
60
N.A.
33.3
N.A.
6.6
33.3
P-Site Similarity:
100
40
33.3
100
N.A.
46.6
100
N.A.
93.3
80
26.6
80
N.A.
40
N.A.
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
39
0
0
31
0
0
8
0
16
8
0
0
85
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
16
0
8
0
8
0
0
16
39
0
0
0
0
8
8
% D
% Glu:
8
24
0
16
16
8
24
16
47
0
0
0
0
0
0
% E
% Phe:
0
0
24
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
47
0
0
0
0
0
0
0
0
% G
% His:
0
0
16
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
39
16
0
8
0
47
8
8
0
0
77
47
0
0
39
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
0
8
16
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
8
0
8
0
31
% M
% Asn:
16
0
8
31
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
16
0
0
8
0
0
0
0
0
0
0
0
0
0
16
% R
% Ser:
0
8
0
16
47
0
0
31
0
0
0
0
0
0
0
% S
% Thr:
0
0
39
0
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
8
8
0
31
8
0
8
0
0
8
77
8
8
% V
% Trp:
8
0
0
0
0
8
8
0
0
77
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
31
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _