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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP2
All Species:
12.73
Human Site:
S223
Identified Species:
23.33
UniProt:
Q9UGN5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGN5
NP_001036083.1
583
66206
S223
E
E
T
K
K
E
E
S
L
K
S
P
L
K
P
Chimpanzee
Pan troglodytes
XP_001137329
531
60196
S223
E
E
T
K
K
E
E
S
L
K
S
P
L
K
P
Rhesus Macaque
Macaca mulatta
XP_001088314
583
66217
S223
E
E
T
K
K
E
E
S
L
K
S
P
L
K
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
L217
L
D
L
R
V
Q
E
L
L
K
L
I
C
N
V
Rat
Rattus norvegicus
P27008
1014
112642
G660
K
K
L
A
V
K
P
G
T
K
S
K
L
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P26446
1011
113502
G657
R
K
L
T
V
S
A
G
T
K
S
K
L
A
K
Frog
Xenopus laevis
P31669
998
111108
G643
K
K
L
S
V
G
A
G
T
K
S
K
L
A
K
Zebra Danio
Brachydanio rerio
XP_001923129
647
72923
Q292
A
V
V
P
S
A
T
Q
K
K
P
C
Q
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35875
994
113773
T644
K
H
E
S
H
F
F
T
S
K
L
E
I
S
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4H4
945
107988
S585
D
T
E
I
T
P
G
S
K
T
L
L
P
K
S
Sea Urchin
Strong. purpuratus
XP_001199118
736
83866
E383
E
S
S
G
D
A
K
E
S
K
P
K
V
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
Q298
E
K
G
S
I
T
D
Q
I
K
E
T
K
L
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
S277
P
V
N
N
D
I
P
S
S
S
S
E
V
K
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
97.4
N.A.
N.A.
84.2
27.1
N.A.
N.A.
27.9
25.7
55.6
N.A.
26.6
N.A.
23.8
42.5
Protein Similarity:
100
91
98.4
N.A.
N.A.
90.7
40.2
N.A.
N.A.
40.9
41
70.9
N.A.
40.8
N.A.
38.7
56.2
P-Site Identity:
100
100
100
N.A.
N.A.
20
20
N.A.
N.A.
20
20
6.6
N.A.
6.6
N.A.
13.3
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
40
40
N.A.
N.A.
26.6
33.3
6.6
N.A.
26.6
N.A.
20
33.3
Percent
Protein Identity:
N.A.
42.5
N.A.
41.6
N.A.
N.A.
Protein Similarity:
N.A.
56.8
N.A.
57.6
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
16
16
0
0
0
0
0
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% C
% Asp:
8
8
0
0
16
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
39
24
16
0
0
24
31
8
0
0
8
16
0
0
8
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
8
8
24
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
8
0
0
8
0
0
8
8
0
0
% I
% Lys:
24
31
0
24
24
8
8
0
16
85
0
31
8
39
24
% K
% Leu:
8
0
31
0
0
0
0
8
31
0
24
8
47
16
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
0
0
0
0
8
8
% N
% Pro:
8
0
0
8
0
8
16
0
0
0
16
24
8
16
31
% P
% Gln:
0
0
0
0
0
8
0
16
0
0
0
0
8
0
0
% Q
% Arg:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
24
8
8
0
39
24
8
54
0
0
8
16
% S
% Thr:
0
8
24
8
8
8
8
8
24
8
0
8
0
0
0
% T
% Val:
0
16
8
0
31
0
0
0
0
0
0
0
16
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _