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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP2
All Species:
23.03
Human Site:
S514
Identified Species:
42.22
UniProt:
Q9UGN5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGN5
NP_001036083.1
583
66206
S514
G
L
L
Q
G
K
H
S
T
K
G
L
G
K
M
Chimpanzee
Pan troglodytes
XP_001137329
531
60196
Y462
Y
M
F
G
K
G
I
Y
F
A
D
M
S
S
K
Rhesus Macaque
Macaca mulatta
XP_001088314
583
66217
S514
G
L
L
Q
G
K
H
S
T
K
G
L
G
K
M
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
S490
G
L
L
R
G
K
H
S
T
K
G
M
G
K
M
Rat
Rattus norvegicus
P27008
1014
112642
S947
K
L
P
K
G
K
H
S
V
K
G
L
G
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P26446
1011
113502
S944
K
L
P
K
G
K
H
S
V
K
G
L
G
K
T
Frog
Xenopus laevis
P31669
998
111108
S930
K
L
P
K
G
K
H
S
V
K
G
L
G
R
T
Zebra Danio
Brachydanio rerio
XP_001923129
647
72923
S578
Q
L
P
S
G
K
H
S
T
K
G
L
G
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35875
994
113773
K927
I
N
K
L
S
N
N
K
H
S
C
F
G
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4H4
945
107988
Q876
P
A
G
F
Q
S
V
Q
G
L
G
R
Q
C
P
Sea Urchin
Strong. purpuratus
XP_001199118
736
83866
V670
L
P
A
G
K
Q
S
V
K
G
L
G
S
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
K585
A
N
N
L
P
K
G
K
L
R
S
K
G
V
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
K570
A
D
N
L
P
P
G
K
L
S
T
K
G
V
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
97.4
N.A.
N.A.
84.2
27.1
N.A.
N.A.
27.9
25.7
55.6
N.A.
26.6
N.A.
23.8
42.5
Protein Similarity:
100
91
98.4
N.A.
N.A.
90.7
40.2
N.A.
N.A.
40.9
41
70.9
N.A.
40.8
N.A.
38.7
56.2
P-Site Identity:
100
0
100
N.A.
N.A.
86.6
66.6
N.A.
N.A.
66.6
60
66.6
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
13.3
100
N.A.
N.A.
100
73.3
N.A.
N.A.
73.3
73.3
73.3
N.A.
20
N.A.
6.6
6.6
Percent
Protein Identity:
N.A.
42.5
N.A.
41.6
N.A.
N.A.
Protein Similarity:
N.A.
56.8
N.A.
57.6
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
8
0
0
0
0
0
0
8
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
8
0
0
0
0
8
0
0
8
0
0
0
% F
% Gly:
24
0
8
16
54
8
16
0
8
8
62
8
77
0
24
% G
% His:
0
0
0
0
0
0
54
0
8
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
24
0
8
24
16
62
0
24
8
54
0
16
0
39
8
% K
% Leu:
8
54
24
24
0
0
0
0
16
8
8
47
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
16
0
0
24
% M
% Asn:
0
16
16
0
0
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
31
0
16
8
0
0
0
0
0
0
0
0
8
% P
% Gln:
8
0
0
16
8
8
0
8
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
8
0
8
0
16
0
% R
% Ser:
0
0
0
8
8
8
8
54
0
16
8
0
16
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
31
0
8
0
0
0
31
% T
% Val:
0
0
0
0
0
0
8
8
24
0
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _