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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP2
All Species:
15.45
Human Site:
Y260
Identified Species:
28.33
UniProt:
Q9UGN5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGN5
NP_001036083.1
583
66206
Y260
E
M
M
M
E
M
K
Y
N
T
K
K
A
P
L
Chimpanzee
Pan troglodytes
XP_001137329
531
60196
A250
K
L
I
C
N
V
Q
A
M
E
E
M
M
M
E
Rhesus Macaque
Macaca mulatta
XP_001088314
583
66217
Y260
E
M
M
M
E
M
K
Y
N
T
K
K
A
P
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
L246
K
R
A
P
L
G
K
L
T
V
A
Q
I
K
A
Rat
Rattus norvegicus
P27008
1014
112642
I691
K
A
L
V
E
Y
E
I
D
L
Q
K
M
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P26446
1011
113502
I688
K
A
M
V
E
F
E
I
D
L
Q
K
M
P
L
Frog
Xenopus laevis
P31669
998
111108
I674
K
A
M
V
E
F
E
I
D
L
Q
K
M
P
L
Zebra Danio
Brachydanio rerio
XP_001923129
647
72923
F324
E
C
V
L
E
M
K
F
D
T
K
K
A
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35875
994
113773
I673
K
T
L
M
E
F
H
I
D
M
D
K
M
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4H4
945
107988
M615
S
A
L
K
S
F
E
M
D
V
N
K
M
P
L
Sea Urchin
Strong. purpuratus
XP_001199118
736
83866
Y418
D
L
V
I
E
M
K
Y
D
T
Q
K
A
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
Y330
Q
R
M
V
E
I
G
Y
N
A
E
K
L
P
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
Y315
Q
H
M
M
E
I
G
Y
N
A
N
K
L
P
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
97.4
N.A.
N.A.
84.2
27.1
N.A.
N.A.
27.9
25.7
55.6
N.A.
26.6
N.A.
23.8
42.5
Protein Similarity:
100
91
98.4
N.A.
N.A.
90.7
40.2
N.A.
N.A.
40.9
41
70.9
N.A.
40.8
N.A.
38.7
56.2
P-Site Identity:
100
0
100
N.A.
N.A.
6.6
26.6
N.A.
N.A.
33.3
33.3
66.6
N.A.
33.3
N.A.
20
60
P-Site Similarity:
100
40
100
N.A.
N.A.
20
66.6
N.A.
N.A.
66.6
66.6
93.3
N.A.
53.3
N.A.
40
100
Percent
Protein Identity:
N.A.
42.5
N.A.
41.6
N.A.
N.A.
Protein Similarity:
N.A.
56.8
N.A.
57.6
N.A.
N.A.
P-Site Identity:
N.A.
46.6
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
31
8
0
0
0
0
8
0
16
8
0
31
0
8
% A
% Cys:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
54
0
8
0
0
0
0
% D
% Glu:
24
0
0
0
77
0
31
0
0
8
16
0
0
0
8
% E
% Phe:
0
0
0
0
0
31
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
16
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
16
0
31
0
0
0
0
8
0
0
% I
% Lys:
47
0
0
8
0
0
39
0
0
0
24
85
0
8
0
% K
% Leu:
0
16
24
8
8
0
0
8
0
24
0
0
16
0
85
% L
% Met:
0
16
47
31
0
31
0
8
8
8
0
8
47
8
0
% M
% Asn:
0
0
0
0
8
0
0
0
31
0
16
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
85
0
% P
% Gln:
16
0
0
0
0
0
8
0
0
0
31
8
0
0
0
% Q
% Arg:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
8
31
0
0
0
0
0
% T
% Val:
0
0
16
31
0
8
0
0
0
16
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _