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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PARP2
All Species:
34.55
Human Site:
Y397
Identified Species:
63.33
UniProt:
Q9UGN5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGN5
NP_001036083.1
583
66206
Y397
H
A
P
T
H
S
D
Y
T
M
T
L
L
D
L
Chimpanzee
Pan troglodytes
XP_001137329
531
60196
P371
N
L
H
C
A
L
R
P
L
D
H
E
S
Y
E
Rhesus Macaque
Macaca mulatta
XP_001088314
583
66217
Y397
H
A
P
T
H
S
D
Y
T
M
T
L
L
D
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88554
559
63378
Y373
H
A
P
T
H
K
D
Y
T
M
T
L
L
D
V
Rat
Rattus norvegicus
P27008
1014
112642
Y829
H
A
T
T
H
N
A
Y
D
L
E
V
I
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P26446
1011
113502
Y826
H
A
A
T
H
N
A
Y
D
L
K
V
V
E
I
Frog
Xenopus laevis
P31669
998
111108
Y812
H
A
D
T
H
N
A
Y
D
L
E
V
L
E
I
Zebra Danio
Brachydanio rerio
XP_001923129
647
72923
Y461
H
A
P
T
H
T
D
Y
T
M
T
L
L
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35875
994
113773
Y811
H
A
S
T
H
K
S
Y
D
L
K
I
V
D
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4H4
945
107988
K758
H
G
A
T
H
D
L
K
V
E
L
I
D
I
L
Sea Urchin
Strong. purpuratus
XP_001199118
736
83866
Y555
C
Q
P
N
H
P
D
Y
F
L
L
I
F
F
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O50017
653
72977
Y468
H
G
K
T
H
S
G
Y
T
V
D
I
V
Q
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q11207
637
72157
Y453
H
A
K
T
H
S
G
Y
T
V
E
I
A
Q
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.9
97.4
N.A.
N.A.
84.2
27.1
N.A.
N.A.
27.9
25.7
55.6
N.A.
26.6
N.A.
23.8
42.5
Protein Similarity:
100
91
98.4
N.A.
N.A.
90.7
40.2
N.A.
N.A.
40.9
41
70.9
N.A.
40.8
N.A.
38.7
56.2
P-Site Identity:
100
0
100
N.A.
N.A.
86.6
40
N.A.
N.A.
33.3
40
86.6
N.A.
40
N.A.
26.6
26.6
P-Site Similarity:
100
6.6
100
N.A.
N.A.
93.3
73.3
N.A.
N.A.
73.3
73.3
100
N.A.
66.6
N.A.
33.3
46.6
Percent
Protein Identity:
N.A.
42.5
N.A.
41.6
N.A.
N.A.
Protein Similarity:
N.A.
56.8
N.A.
57.6
N.A.
N.A.
P-Site Identity:
N.A.
40
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
70
16
0
8
0
24
0
0
0
0
0
8
0
0
% A
% Cys:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
39
0
31
8
8
0
8
47
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
24
8
0
16
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
0
% F
% Gly:
0
16
0
0
0
0
16
0
0
0
0
0
0
0
0
% G
% His:
85
0
8
0
93
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
39
8
8
39
% I
% Lys:
0
0
16
0
0
16
0
8
0
0
16
0
0
0
0
% K
% Leu:
0
8
0
0
0
8
8
0
8
39
16
31
39
0
31
% L
% Met:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
24
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
39
0
0
8
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
16
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
31
8
0
0
0
0
0
8
0
0
% S
% Thr:
0
0
8
85
0
8
0
0
47
0
31
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
16
0
24
24
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _