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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIMD1 All Species: 15.76
Human Site: S421 Identified Species: 26.67
UniProt: Q9UGP4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UGP4 NP_055055.1 676 72190 S421 L G S V L L D S P S S P R V R
Chimpanzee Pan troglodytes XP_001147894 676 72166 S421 L G S V L L D S P S S P R V R
Rhesus Macaque Macaca mulatta XP_001114527 681 72493 S421 L G P V L L E S P S S P R V R
Dog Lupus familis XP_541912 655 69604 P404 L P E S P S P P R V R L P C Q
Cat Felis silvestris
Mouse Mus musculus Q9QXD8 668 71403 S413 L E P V L P G S P T P S R V R
Rat Rattus norvegicus Q5U2Z2 548 58063 E321 I E P S G L E E S P G S F V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513540 700 74650 G436 R S S P P P E G G D G N R H P
Chicken Gallus gallus Q5F464 604 65121 P377 S G P T S S T P A F R P E D E
Frog Xenopus laevis A9LS46 690 75317 N424 S G A V A S Y N F S S A K G S
Zebra Danio Brachydanio rerio A8DZE6 648 70883 V401 R F K L P Y Q V T P S R D S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572930 728 77943 S452 V A T S P T P S Q G S T A V N
Honey Bee Apis mellifera XP_391978 881 97801 T562 Q I Q T P V T T G T P T T T E
Nematode Worm Caenorhab. elegans Q09476 413 46434 Q186 C G K P I I G Q V V I A L G K
Sea Urchin Strong. purpuratus XP_792799 904 97329 S458 N A S N S K Q S Q A S V R P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 91.7 79.1 N.A. 77.6 32.9 N.A. 58.1 27.2 37.8 39 N.A. 32.6 30.3 20.7 28.6
Protein Similarity: 100 99.6 93.5 83.2 N.A. 80.9 47.6 N.A. 66.5 41.5 50.1 52 N.A. 46.4 45 32.5 40.2
P-Site Identity: 100 100 86.6 6.6 N.A. 53.3 13.3 N.A. 13.3 13.3 26.6 6.6 N.A. 20 0 6.6 26.6
P-Site Similarity: 100 100 93.3 13.3 N.A. 60 26.6 N.A. 20 13.3 46.6 13.3 N.A. 33.3 20 26.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 8 0 8 0 0 0 8 8 0 15 8 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 15 0 0 8 0 0 8 8 0 % D
% Glu: 0 15 8 0 0 0 22 8 0 0 0 0 8 0 15 % E
% Phe: 0 8 0 0 0 0 0 0 8 8 0 0 8 0 0 % F
% Gly: 0 43 0 0 8 0 15 8 15 8 15 0 0 15 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 8 8 0 0 8 8 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 15 0 0 8 0 0 0 0 0 0 8 0 15 % K
% Leu: 36 0 0 8 29 29 0 0 0 0 0 8 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 8 0 0 0 8 0 0 0 8 0 0 8 % N
% Pro: 0 8 29 15 36 15 15 15 29 15 15 29 8 8 15 % P
% Gln: 8 0 8 0 0 0 15 8 15 0 0 0 0 0 8 % Q
% Arg: 15 0 0 0 0 0 0 0 8 0 15 8 43 0 29 % R
% Ser: 15 8 29 22 15 22 0 43 8 29 50 15 0 8 8 % S
% Thr: 0 0 8 15 0 8 15 8 8 15 0 15 8 8 0 % T
% Val: 8 0 0 36 0 8 0 8 8 15 0 8 0 43 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _