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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLL All Species: 18.18
Human Site: T173 Identified Species: 36.36
UniProt: Q9UGP5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UGP5 NP_037406.1 575 63482 T173 L S P P P P P T R P V S P P Q
Chimpanzee Pan troglodytes XP_507992 575 63394 T173 L S P P P P P T R P V S P P Q
Rhesus Macaque Macaca mulatta XP_001110483 575 63575 T173 L P P P P S P T R P V S P P Q
Dog Lupus familis XP_850651 576 63314 T174 L T P P R S A T R P V S P P Q
Cat Felis silvestris
Mouse Mus musculus Q9QXE2 573 62924 T171 L S L S P P H T R A V S P P P
Rat Rattus norvegicus Q5RKI3 573 62383 T171 L S L S P P C T R A V S P P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511409 1156 126349 D187 R L S S P P A D A Q P I S P P
Chicken Gallus gallus XP_001232209 575 63775 D173 N A K A Q L G D S S Q Q N L D
Frog Xenopus laevis O57383 334 38275
Zebra Danio Brachydanio rerio Q6DRD3 336 38547
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785226 410 45521 R20 T N A S N K K R Q K Q N D S G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172522 529 59569 K137 E D Q S S P Q K R T R Y S P D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97 85.4 N.A. 82.4 82.4 N.A. 33.8 66.7 22 21.5 N.A. N.A. N.A. N.A. 20
Protein Similarity: 100 99.6 98.4 91.3 N.A. 88.3 88.8 N.A. 40.2 78 36.7 36.1 N.A. N.A. N.A. N.A. 37.7
P-Site Identity: 100 100 86.6 73.3 N.A. 66.6 66.6 N.A. 20 0 0 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 86.6 80 N.A. 66.6 66.6 N.A. 20 6.6 0 0 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 29.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 9 0 0 17 0 9 17 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 17 0 0 0 0 9 0 17 % D
% Glu: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 0 9 0 0 9 9 9 0 9 0 0 0 0 0 % K
% Leu: 50 9 17 0 0 9 0 0 0 0 0 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 9 0 0 9 0 0 0 0 0 0 9 9 0 0 % N
% Pro: 0 9 34 34 50 50 25 0 0 34 9 0 50 67 25 % P
% Gln: 0 0 9 0 9 0 9 0 9 9 17 9 0 0 34 % Q
% Arg: 9 0 0 0 9 0 0 9 59 0 9 0 0 0 0 % R
% Ser: 0 34 9 42 9 17 0 0 9 9 0 50 17 9 0 % S
% Thr: 9 9 0 0 0 0 0 50 0 9 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _