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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLL All Species: 25.76
Human Site: T553 Identified Species: 51.52
UniProt: Q9UGP5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UGP5 NP_037406.1 575 63482 T553 G P G R V L P T P T E K D V F
Chimpanzee Pan troglodytes XP_507992 575 63394 T553 G P G R V L P T P T E K D V F
Rhesus Macaque Macaca mulatta XP_001110483 575 63575 T553 G P G R V L P T P T E K D V F
Dog Lupus familis XP_850651 576 63314 T554 G P G R V L P T P T E K D V F
Cat Felis silvestris
Mouse Mus musculus Q9QXE2 573 62924 T551 G P G Q V L P T P T E K D V F
Rat Rattus norvegicus Q5RKI3 573 62383 T551 G A G Q V L P T P T E K D V F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511409 1156 126349 V1013 P P A P W L P V P Y A V L Y D
Chicken Gallus gallus XP_001232209 575 63775 T553 A S G H A L P T P T E R D V F
Frog Xenopus laevis O57383 334 38275 D313 A G E P L P I D S E K D I F D
Zebra Danio Brachydanio rerio Q6DRD3 336 38547 D315 A G E P L L V D S E K D I F E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785226 410 45521 L389 S K Q Q L I G L K H Y H E F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_172522 529 59569 L507 R G T A S L K L S T E K Q V F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97 85.4 N.A. 82.4 82.4 N.A. 33.8 66.7 22 21.5 N.A. N.A. N.A. N.A. 20
Protein Similarity: 100 99.6 98.4 91.3 N.A. 88.3 88.8 N.A. 40.2 78 36.7 36.1 N.A. N.A. N.A. N.A. 37.7
P-Site Identity: 100 100 100 100 N.A. 93.3 86.6 N.A. 26.6 66.6 0 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 26.6 73.3 13.3 20 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 29.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 40 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 9 9 9 9 0 0 0 0 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 17 0 0 0 17 59 0 17 % D
% Glu: 0 0 17 0 0 0 0 0 0 17 67 0 9 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 67 % F
% Gly: 50 25 59 0 0 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 9 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 9 9 0 0 0 0 0 17 0 0 % I
% Lys: 0 9 0 0 0 0 9 0 9 0 17 59 0 0 0 % K
% Leu: 0 0 0 0 25 84 0 17 0 0 0 0 9 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 50 0 25 0 9 67 0 67 0 0 0 0 0 0 % P
% Gln: 0 0 9 25 0 0 0 0 0 0 0 0 9 0 0 % Q
% Arg: 9 0 0 34 0 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 9 9 0 0 9 0 0 0 25 0 0 0 0 0 0 % S
% Thr: 0 0 9 0 0 0 0 59 0 67 0 0 0 0 0 % T
% Val: 0 0 0 0 50 0 9 9 0 0 0 9 0 67 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 9 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _