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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC2A6 All Species: 11.21
Human Site: S259 Identified Species: 18.97
UniProt: Q9UGQ3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UGQ3 NP_001138571.1 507 54539 S259 Q D N V R R Q S S R V S W A E
Chimpanzee Pan troglodytes XP_528524 507 54553 S259 Q D N V R R Q S S R V S W A E
Rhesus Macaque Macaca mulatta XP_001118379 480 51222 G239 R A L A W L R G T D A D V H W
Dog Lupus familis XP_548395 507 54801 S259 Q D N V R R Q S T H M S W A E
Cat Felis silvestris
Mouse Mus musculus Q9JIF3 477 51505 V237 E G W E E P P V G A E H Q G F
Rat Rattus norvegicus Q9JJZ1 478 51440 V237 E G W E E P P V G A E H Q G F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520019 470 50144 R230 T A Q S R N G R M S W A E I K
Chicken Gallus gallus P46896 490 54068 S247 L Q E M K E E S R Q M M R E K
Frog Xenopus laevis NP_001087681 465 51027 S225 L K K S S T L S W T E L S Q P
Zebra Danio Brachydanio rerio XP_689092 432 47490 V192 V A G E V P V V I M M L L L C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610694 488 53070 E235 R G K E A D V E P E L K E L M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787337 482 52038 L238 K N Q A M L V L R R L R G P M
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001147831 502 54145 D262 L Q V L R G F D A D I T A E L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FRL3 487 52883 E247 L Q V L R G F E T D I T V E V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 90.3 87.9 N.A. 42.4 43.5 N.A. 67.4 23.8 56.6 49.9 N.A. 32.9 N.A. N.A. 33.3
Protein Similarity: 100 100 91.7 91.9 N.A. 59.9 59.1 N.A. 77.1 43.5 73.3 63.7 N.A. 52 N.A. N.A. 53.6
P-Site Identity: 100 100 0 80 N.A. 0 0 N.A. 6.6 6.6 6.6 0 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 20 93.3 N.A. 6.6 6.6 N.A. 20 46.6 6.6 6.6 N.A. 13.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. 32.5 N.A. 30.5 N.A. N.A.
Protein Similarity: N.A. 54.2 N.A. 51.8 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 0 15 8 0 0 0 8 15 8 8 8 22 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 22 0 0 0 8 0 8 0 22 0 8 0 0 0 % D
% Glu: 15 0 8 29 15 8 8 15 0 8 22 0 15 22 22 % E
% Phe: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 15 % F
% Gly: 0 22 8 0 0 15 8 8 15 0 0 0 8 15 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 15 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 15 0 0 8 0 % I
% Lys: 8 8 15 0 8 0 0 0 0 0 0 8 0 0 15 % K
% Leu: 29 0 8 15 0 15 8 8 0 0 15 15 8 15 8 % L
% Met: 0 0 0 8 8 0 0 0 8 8 22 8 0 0 15 % M
% Asn: 0 8 22 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 22 15 0 8 0 0 0 0 8 8 % P
% Gln: 22 22 15 0 0 0 22 0 0 8 0 0 15 8 0 % Q
% Arg: 15 0 0 0 43 22 8 8 15 22 0 8 8 0 0 % R
% Ser: 0 0 0 15 8 0 0 36 15 8 0 22 8 0 0 % S
% Thr: 8 0 0 0 0 8 0 0 22 8 0 15 0 0 0 % T
% Val: 8 0 15 22 8 0 22 22 0 0 15 0 15 0 8 % V
% Trp: 0 0 15 0 8 0 0 0 8 0 8 0 22 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _