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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC2A6 All Species: 8.79
Human Site: S368 Identified Species: 14.87
UniProt: Q9UGQ3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UGQ3 NP_001138571.1 507 54539 S368 H F G P R P L S P N S T A G L
Chimpanzee Pan troglodytes XP_528524 507 54553 S368 H F G P R P L S P N S T A G L
Rhesus Macaque Macaca mulatta XP_001118379 480 51222 F343 A G R K V L L F V S A A I M F
Dog Lupus familis XP_548395 507 54801 T368 H F G P K P L T P N S T M G L
Cat Felis silvestris
Mouse Mus musculus Q9JIF3 477 51505 F341 M S A F G T Y F K L T Q S L P
Rat Rattus norvegicus Q9JJZ1 478 51440 F341 M S A F G T Y F K L T Q S G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520019 470 50144 P334 L Y V L L T A P R E I H N G T
Chicken Gallus gallus P46896 490 54068 A353 C A I L M T I A L T L L D Q M
Frog Xenopus laevis NP_001087681 465 51027 N329 V H F T V D I N H N S T N R T
Zebra Danio Brachydanio rerio XP_689092 432 47490 P296 L T A I S L E P K Y D A A L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610694 488 53070 D339 K I L L Y V S D I A M I V T L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787337 482 52038 I344 A L L I T G A I G L A V S S A
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001147831 502 54145 I366 G R R I L L I I S S A G M T L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FRL3 487 52883 I351 G R R L L L T I S S V G M T I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 90.3 87.9 N.A. 42.4 43.5 N.A. 67.4 23.8 56.6 49.9 N.A. 32.9 N.A. N.A. 33.3
Protein Similarity: 100 100 91.7 91.9 N.A. 59.9 59.1 N.A. 77.1 43.5 73.3 63.7 N.A. 52 N.A. N.A. 53.6
P-Site Identity: 100 100 6.6 80 N.A. 0 6.6 N.A. 6.6 0 20 6.6 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 20 93.3 N.A. 13.3 20 N.A. 13.3 20 33.3 13.3 N.A. 6.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. 32.5 N.A. 30.5 N.A. N.A.
Protein Similarity: N.A. 54.2 N.A. 51.8 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 26.6 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 22 0 0 0 15 8 0 8 22 15 22 0 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 8 0 0 8 0 8 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % E
% Phe: 0 22 8 15 0 0 0 22 0 0 0 0 0 0 8 % F
% Gly: 15 8 22 0 15 8 0 0 8 0 0 15 0 36 0 % G
% His: 22 8 0 0 0 0 0 0 8 0 0 8 0 0 0 % H
% Ile: 0 8 8 22 0 0 22 22 8 0 8 8 8 0 8 % I
% Lys: 8 0 0 8 8 0 0 0 22 0 0 0 0 0 0 % K
% Leu: 15 8 15 29 22 29 29 0 8 22 8 8 0 15 36 % L
% Met: 15 0 0 0 8 0 0 0 0 0 8 0 22 8 8 % M
% Asn: 0 0 0 0 0 0 0 8 0 29 0 0 15 0 0 % N
% Pro: 0 0 0 22 0 22 0 15 22 0 0 0 0 0 15 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 15 0 8 0 % Q
% Arg: 0 15 22 0 15 0 0 0 8 0 0 0 0 8 0 % R
% Ser: 0 15 0 0 8 0 8 15 15 22 29 0 22 8 0 % S
% Thr: 0 8 0 8 8 29 8 8 0 8 15 29 0 22 15 % T
% Val: 8 0 8 0 15 8 0 0 8 0 8 8 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 8 0 15 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _