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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC2A6
All Species:
18.79
Human Site:
S490
Identified Species:
31.79
UniProt:
Q9UGQ3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGQ3
NP_001138571.1
507
54539
S490
V
P
E
T
K
G
R
S
L
E
Q
I
E
S
F
Chimpanzee
Pan troglodytes
XP_528524
507
54553
S490
V
P
E
T
K
G
R
S
L
E
Q
I
E
S
F
Rhesus Macaque
Macaca mulatta
XP_001118379
480
51222
P464
V
S
A
Q
P
R
A
P
R
P
S
L
T
D
Q
Dog
Lupus familis
XP_548395
507
54801
S490
V
P
E
T
K
G
R
S
L
E
Q
I
E
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIF3
477
51505
E461
F
T
L
T
V
V
P
E
T
K
G
R
T
L
E
Rat
Rattus norvegicus
Q9JJZ1
478
51440
P461
L
F
T
L
T
F
V
P
E
T
K
G
R
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520019
470
50144
P454
I
F
T
G
R
C
V
P
G
T
E
G
L
L
L
Chicken
Gallus gallus
P46896
490
54068
S474
R
Q
G
G
A
S
Q
S
D
K
T
P
D
E
F
Frog
Xenopus laevis
NP_001087681
465
51027
L449
P
E
T
K
G
R
T
L
E
Q
I
E
S
Y
F
Zebra Danio
Brachydanio rerio
XP_689092
432
47490
E416
T
K
G
R
T
L
E
E
I
E
N
Y
F
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610694
488
53070
S461
V
P
E
T
R
G
K
S
L
E
E
I
E
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787337
482
52038
S466
V
P
E
T
K
G
R
S
L
E
E
I
E
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001147831
502
54145
V486
L
V
F
V
I
V
W
V
P
E
T
K
G
R
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FRL3
487
52883
V471
V
V
F
V
T
L
W
V
P
E
T
K
G
K
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
90.3
87.9
N.A.
42.4
43.5
N.A.
67.4
23.8
56.6
49.9
N.A.
32.9
N.A.
N.A.
33.3
Protein Similarity:
100
100
91.7
91.9
N.A.
59.9
59.1
N.A.
77.1
43.5
73.3
63.7
N.A.
52
N.A.
N.A.
53.6
P-Site Identity:
100
100
6.6
100
N.A.
6.6
0
N.A.
0
13.3
6.6
6.6
N.A.
66.6
N.A.
N.A.
80
P-Site Similarity:
100
100
13.3
100
N.A.
13.3
20
N.A.
20
33.3
13.3
13.3
N.A.
86.6
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
32.5
N.A.
30.5
N.A.
N.A.
Protein Similarity:
N.A.
54.2
N.A.
51.8
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
0
8
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
0
% D
% Glu:
0
8
36
0
0
0
8
15
15
58
22
8
36
8
8
% E
% Phe:
8
15
15
0
0
8
0
0
0
0
0
0
8
0
36
% F
% Gly:
0
0
15
15
8
36
0
0
8
0
8
15
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
8
0
8
36
0
0
0
% I
% Lys:
0
8
0
8
29
0
8
0
0
15
8
15
0
8
8
% K
% Leu:
15
0
8
8
0
15
0
8
36
0
0
8
8
15
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
8
36
0
0
8
0
8
22
15
8
0
8
0
0
0
% P
% Gln:
0
8
0
8
0
0
8
0
0
8
22
0
0
0
8
% Q
% Arg:
8
0
0
8
15
15
29
0
8
0
0
8
8
22
0
% R
% Ser:
0
8
0
0
0
8
0
43
0
0
8
0
8
22
8
% S
% Thr:
8
8
22
43
22
0
8
0
8
15
22
0
15
8
22
% T
% Val:
50
15
0
15
8
15
15
15
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _