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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC2A6 All Species: 17.27
Human Site: S79 Identified Species: 29.23
UniProt: Q9UGQ3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UGQ3 NP_001138571.1 507 54539 S79 P D L H L T K S Q A S W F G S
Chimpanzee Pan troglodytes XP_528524 507 54553 S79 P D L H L T K S Q A S W F G S
Rhesus Macaque Macaca mulatta XP_001118379 480 51222 S79 P D L H L T K S Q A S W F G S
Dog Lupus familis XP_548395 507 54801 A79 P D L K L T K A Q A S W F G S
Cat Felis silvestris
Mouse Mus musculus Q9JIF3 477 51505 T77 S W F G A V V T L G A A A G G
Rat Rattus norvegicus Q9JJZ1 478 51440 T77 S W F G A V V T L G A A A G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520019 470 50144 M69 A A G G L S A M L L N D L L G
Chicken Gallus gallus P46896 490 54068 G74 S V A I F S V G G M I G S F S
Frog Xenopus laevis NP_001087681 465 51027 N65 G I S S M F L N D R L G R K L
Zebra Danio Brachydanio rerio XP_689092 432 47490 A32 L Y L A V F S A V L G N F N F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610694 488 53070 V74 T K D A G S W V G G I M P L A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787337 482 52038 K74 Y S S P A L P K I A F P T S D
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001147831 502 54145 S100 R D L N L S I S E F S V F G S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FRL3 487 52883 S85 K D L G L T V S E Y S V F G S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 90.3 87.9 N.A. 42.4 43.5 N.A. 67.4 23.8 56.6 49.9 N.A. 32.9 N.A. N.A. 33.3
Protein Similarity: 100 100 91.7 91.9 N.A. 59.9 59.1 N.A. 77.1 43.5 73.3 63.7 N.A. 52 N.A. N.A. 53.6
P-Site Identity: 100 100 100 86.6 N.A. 6.6 6.6 N.A. 6.6 6.6 0 13.3 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 20 20 N.A. 20 13.3 13.3 26.6 N.A. 13.3 N.A. N.A. 6.6
Percent
Protein Identity: N.A. 32.5 N.A. 30.5 N.A. N.A.
Protein Similarity: N.A. 54.2 N.A. 51.8 N.A. N.A.
P-Site Identity: N.A. 53.3 N.A. 60 N.A. N.A.
P-Site Similarity: N.A. 73.3 N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 15 22 0 8 15 0 36 15 15 15 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 43 8 0 0 0 0 0 8 0 0 8 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % E
% Phe: 0 0 15 0 8 15 0 0 0 8 8 0 50 8 8 % F
% Gly: 8 0 8 29 8 0 0 8 15 22 8 15 0 58 22 % G
% His: 0 0 0 22 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 0 0 8 0 8 0 15 0 0 0 0 % I
% Lys: 8 8 0 8 0 0 29 8 0 0 0 0 0 8 0 % K
% Leu: 8 0 50 0 50 8 8 0 22 15 8 0 8 15 8 % L
% Met: 0 0 0 0 8 0 0 8 0 8 0 8 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 8 0 0 8 8 0 8 0 % N
% Pro: 29 0 0 8 0 0 8 0 0 0 0 8 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 29 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % R
% Ser: 22 8 15 8 0 29 8 36 0 0 43 0 8 8 50 % S
% Thr: 8 0 0 0 0 36 0 15 0 0 0 0 8 0 0 % T
% Val: 0 8 0 0 8 15 29 8 8 0 0 15 0 0 0 % V
% Trp: 0 15 0 0 0 0 8 0 0 0 0 29 0 0 0 % W
% Tyr: 8 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _