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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC2A6 All Species: 10
Human Site: T149 Identified Species: 16.92
UniProt: Q9UGQ3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UGQ3 NP_001138571.1 507 54539 T149 T G F A G G L T A A C I P V Y
Chimpanzee Pan troglodytes XP_528524 507 54553 T149 T G F A G G L T A A C I P V Y
Rhesus Macaque Macaca mulatta XP_001118379 480 51222 G147 T L T G F A G G L T A A C I P
Dog Lupus familis XP_548395 507 54801 T149 T G F A G G L T A A C I P V Y
Cat Felis silvestris
Mouse Mus musculus Q9JIF3 477 51505 I145 S L V A P V Y I S E I A Y P A
Rat Rattus norvegicus Q9JJZ1 478 51440 I145 S L V A P V Y I S E I A Y P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520019 470 50144 L138 H P R V R G A L G A T P Q I M
Chicken Gallus gallus P46896 490 54068 Y142 T T G F V P M Y V G E V S P T
Frog Xenopus laevis NP_001087681 465 51027 A133 G V R G G L G A C P Q I M A V
Zebra Danio Brachydanio rerio XP_689092 432 47490 M100 V G R K I S I M I S G L P S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610694 488 53070 L143 V G I A S L S L P V Y L G E T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787337 482 52038 I144 I N L Y C G R I L T G M G C G
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001147831 502 54145 I170 E G F G V G I I S Y V V P V Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FRL3 487 52883 I155 E G F G V G I I S Y T V P V Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 90.3 87.9 N.A. 42.4 43.5 N.A. 67.4 23.8 56.6 49.9 N.A. 32.9 N.A. N.A. 33.3
Protein Similarity: 100 100 91.7 91.9 N.A. 59.9 59.1 N.A. 77.1 43.5 73.3 63.7 N.A. 52 N.A. N.A. 53.6
P-Site Identity: 100 100 6.6 100 N.A. 6.6 6.6 N.A. 13.3 6.6 13.3 13.3 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 100 13.3 100 N.A. 20 20 N.A. 20 20 13.3 33.3 N.A. 20 N.A. N.A. 13.3
Percent
Protein Identity: N.A. 32.5 N.A. 30.5 N.A. N.A.
Protein Similarity: N.A. 54.2 N.A. 51.8 N.A. N.A.
P-Site Identity: N.A. 40 N.A. 40 N.A. N.A.
P-Site Similarity: N.A. 60 N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 43 0 8 8 8 22 29 8 22 0 8 15 % A
% Cys: 0 0 0 0 8 0 0 0 8 0 22 0 8 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 15 0 0 0 0 0 0 0 0 15 8 0 0 8 0 % E
% Phe: 0 0 36 8 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 50 8 29 29 50 15 8 8 8 15 0 15 0 8 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 8 0 8 0 22 36 8 0 15 29 0 15 0 % I
% Lys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 22 8 0 0 15 22 15 15 0 0 15 0 0 0 % L
% Met: 0 0 0 0 0 0 8 8 0 0 0 8 8 0 8 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 0 15 8 0 0 8 8 0 8 43 22 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % Q
% Arg: 0 0 22 0 8 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 15 0 0 0 8 8 8 0 29 8 0 0 8 8 0 % S
% Thr: 36 8 8 0 0 0 0 22 0 15 15 0 0 0 15 % T
% Val: 15 8 15 8 22 15 0 0 8 8 8 22 0 36 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 15 8 0 15 8 0 15 0 36 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _