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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC2A6 All Species: 16.36
Human Site: T486 Identified Species: 27.69
UniProt: Q9UGQ3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UGQ3 NP_001138571.1 507 54539 T486 T G C C V P E T K G R S L E Q
Chimpanzee Pan troglodytes XP_528524 507 54553 T486 T G C C V P E T K G R S L E Q
Rhesus Macaque Macaca mulatta XP_001118379 480 51222 Q460 L P V V V S A Q P R A P R P S
Dog Lupus familis XP_548395 507 54801 T486 T G C C V P E T K G R S L E Q
Cat Felis silvestris
Mouse Mus musculus Q9JIF3 477 51505 T457 L S V L F T L T V V P E T K G
Rat Rattus norvegicus Q9JJZ1 478 51440 L457 I L S V L F T L T F V P E T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520019 470 50144 G450 L V N L I F T G R C V P G T E
Chicken Gallus gallus P46896 490 54068 G470 A Y R F R Q G G A S Q S D K T
Frog Xenopus laevis NP_001087681 465 51027 K445 Y F F V P E T K G R T L E Q I
Zebra Danio Brachydanio rerio XP_689092 432 47490 R412 C V P E T K G R T L E E I E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610694 488 53070 T457 V I I F V P E T R G K S L E E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787337 482 52038 T462 V F F F V P E T K G R S L E E
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001147831 502 54145 V482 S A F T L V F V I V W V P E T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FRL3 487 52883 V467 C A F T V V F V T L W V P E T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 90.3 87.9 N.A. 42.4 43.5 N.A. 67.4 23.8 56.6 49.9 N.A. 32.9 N.A. N.A. 33.3
Protein Similarity: 100 100 91.7 91.9 N.A. 59.9 59.1 N.A. 77.1 43.5 73.3 63.7 N.A. 52 N.A. N.A. 53.6
P-Site Identity: 100 100 6.6 100 N.A. 6.6 0 N.A. 0 6.6 0 6.6 N.A. 53.3 N.A. N.A. 66.6
P-Site Similarity: 100 100 6.6 100 N.A. 13.3 13.3 N.A. 20 20 6.6 13.3 N.A. 73.3 N.A. N.A. 73.3
Percent
Protein Identity: N.A. 32.5 N.A. 30.5 N.A. N.A.
Protein Similarity: N.A. 54.2 N.A. 51.8 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. 20 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 15 0 0 0 0 8 0 8 0 8 0 0 0 0 % A
% Cys: 15 0 22 22 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 0 8 0 8 36 0 0 0 8 15 15 58 22 % E
% Phe: 0 15 29 22 8 15 15 0 0 8 0 0 0 0 0 % F
% Gly: 0 22 0 0 0 0 15 15 8 36 0 0 8 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 8 0 8 0 0 0 8 0 0 0 8 0 8 % I
% Lys: 0 0 0 0 0 8 0 8 29 0 8 0 0 15 8 % K
% Leu: 22 8 0 15 15 0 8 8 0 15 0 8 36 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 8 8 0 8 36 0 0 8 0 8 22 15 8 0 % P
% Gln: 0 0 0 0 0 8 0 8 0 0 8 0 0 8 22 % Q
% Arg: 0 0 8 0 8 0 0 8 15 15 29 0 8 0 0 % R
% Ser: 8 8 8 0 0 8 0 0 0 8 0 43 0 0 8 % S
% Thr: 22 0 0 15 8 8 22 43 22 0 8 0 8 15 22 % T
% Val: 15 15 15 22 50 15 0 15 8 15 15 15 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % W
% Tyr: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _