KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMGXB4
All Species:
8.79
Human Site:
S143
Identified Species:
32.22
UniProt:
Q9UGU5
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UGU5
NP_001003681.1
601
65712
S143
G
S
S
S
H
S
E
S
K
K
E
H
H
R
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113091
601
65745
S143
G
S
S
S
H
S
E
S
K
K
E
H
H
R
K
Dog
Lupus familis
XP_850802
600
65501
S143
S
S
S
S
H
S
E
S
K
K
E
H
H
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6WKW9
554
60891
A117
K
A
I
T
S
P
Q
A
D
T
S
T
T
H
P
Zebra Danio
Brachydanio rerio
NP_001120984
624
68023
P142
A
T
G
S
E
P
P
P
H
L
H
K
K
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392763
465
52136
A27
L
V
E
Q
Q
S
N
A
M
D
M
F
V
T
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780797
585
65426
K141
K
K
D
A
D
K
A
K
V
K
E
E
P
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
94.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
56.4
46.1
N.A.
N.A.
24.1
N.A.
23.4
Protein Similarity:
100
N.A.
99
95.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
67
58.8
N.A.
N.A.
41.5
N.A.
41.2
P-Site Identity:
100
N.A.
100
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
6.6
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
13.3
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
0
15
0
0
15
29
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
15
0
0
0
15
15
0
0
0
0
0
% D
% Glu:
0
0
15
0
15
0
43
0
0
0
58
15
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% F
% Gly:
29
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
43
0
0
0
15
0
15
43
43
15
0
% H
% Ile:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
15
% I
% Lys:
29
15
0
0
0
15
0
15
43
58
0
15
15
0
43
% K
% Leu:
15
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
15
0
15
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
29
15
15
0
0
0
0
15
15
29
% P
% Gln:
0
0
0
15
15
0
15
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
43
0
% R
% Ser:
15
43
43
58
15
58
0
43
0
0
15
0
0
0
15
% S
% Thr:
0
15
0
15
0
0
0
0
0
15
0
15
15
29
0
% T
% Val:
0
15
0
0
0
0
0
0
15
0
0
0
15
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _