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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NDRG3 All Species: 19.39
Human Site: S333 Identified Species: 47.41
UniProt: Q9UGV2 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UGV2 NP_071922.2 375 41409 S333 R S R T H S T S S S L G S G E
Chimpanzee Pan troglodytes A5A6K6 357 39342 R315 M T R L S R S R T A S L T S A
Rhesus Macaque Macaca mulatta XP_001088529 394 42883 S332 R S R T A S G S S V T S L D G
Dog Lupus familis XP_865665 366 40058 S324 R S R T H S T S S S I G S G E
Cat Felis silvestris
Mouse Mus musculus Q9QYF9 375 41536 S333 R S R T H S T S S S I G S G E
Rat Rattus norvegicus Q6AYR2 375 41488 S333 R S R T H S T S S S I G S G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417315 387 42477 S333 T E S V P A A S M T R L M R S
Frog Xenopus laevis Q6GQL1 375 41290 S333 R S R T H S A S S S G S M E I
Zebra Danio Brachydanio rerio Q5PR98 368 40449 R327 M T R L S R S R T T S L S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O02485 325 35573 V284 L L C K G C G V L S G V A I P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.5 62.1 90.1 N.A. 96 96.5 N.A. N.A. 81.6 75.1 54.9 N.A. N.A. N.A. 26.1 N.A.
Protein Similarity: 100 71.1 76.1 92.8 N.A. 98.4 98.6 N.A. N.A. 87.5 86.6 70.6 N.A. N.A. N.A. 43.2 N.A.
P-Site Identity: 100 6.6 46.6 93.3 N.A. 93.3 93.3 N.A. N.A. 6.6 60 13.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 40 46.6 100 N.A. 100 100 N.A. N.A. 20 60 40 N.A. N.A. N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 10 20 0 0 10 0 0 10 0 10 % A
% Cys: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 40 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 20 0 0 0 20 40 0 40 10 % G
% His: 0 0 0 0 50 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 30 0 0 10 10 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 10 0 20 0 0 0 0 10 0 10 30 10 0 0 % L
% Met: 20 0 0 0 0 0 0 0 10 0 0 0 20 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 60 0 80 0 0 20 0 20 0 0 10 0 0 10 0 % R
% Ser: 0 60 10 0 20 60 20 70 60 60 20 20 50 20 20 % S
% Thr: 10 20 0 60 0 0 40 0 20 20 10 0 10 0 0 % T
% Val: 0 0 0 10 0 0 0 10 0 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _