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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHL3 All Species: 26.67
Human Site: S410 Identified Species: 58.67
UniProt: Q9UH77 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UH77 NP_059111.2 587 64970 S410 D G S T G L A S V E A Y S Y K
Chimpanzee Pan troglodytes XP_001169820 555 61472 K385 S V E A Y S Y K T N E W F F V
Rhesus Macaque Macaca mulatta XP_001112192 587 64972 S410 D G S T G L A S V E A Y S Y K
Dog Lupus familis XP_538644 718 78851 S408 D G S T G L A S V E A Y S Y K
Cat Felis silvestris
Mouse Mus musculus Q8JZP3 593 65964 S416 D G S T G L S S V E A Y N I K
Rat Rattus norvegicus Q8K430 640 69714 S450 D G A S C L N S A E R Y D P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414621 586 65074 S409 D G S T G L A S V E A Y S Y K
Frog Xenopus laevis Q6NRH0 564 63190 H389 G F D G S R R H T S M E R Y D
Zebra Danio Brachydanio rerio Q5U374 564 62914 H389 G F D G S R R H T S M E R Y D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q04652 1477 159964 S512 D G T T G L S S A E M Y D P K
Honey Bee Apis mellifera XP_393674 1049 117222 S438 D G S T G L N S A E V Y D P R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.5 99.3 79.9 N.A. 76 43.2 N.A. N.A. 94.5 39.5 39.5 N.A. 24.7 36.7 N.A. N.A.
Protein Similarity: 100 94.5 99.4 80.9 N.A. 87.5 59.3 N.A. N.A. 97.9 58.4 58.2 N.A. 31.7 45.7 N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 80 40 N.A. N.A. 100 6.6 6.6 N.A. 60 60 N.A. N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 93.3 53.3 N.A. N.A. 100 6.6 6.6 N.A. 73.3 66.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 37 0 28 0 46 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 73 0 19 0 0 0 0 0 0 0 0 0 28 0 19 % D
% Glu: 0 0 10 0 0 0 0 0 0 73 10 19 0 0 0 % E
% Phe: 0 19 0 0 0 0 0 0 0 0 0 0 10 10 0 % F
% Gly: 19 73 0 19 64 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 19 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 55 % K
% Leu: 0 0 0 0 0 73 0 0 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 28 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 19 0 0 10 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 28 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 19 19 0 0 0 10 0 19 0 10 % R
% Ser: 10 0 55 10 19 10 19 73 0 19 0 0 37 0 0 % S
% Thr: 0 0 10 64 0 0 0 0 28 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 46 0 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 10 0 10 0 0 0 0 73 0 55 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _