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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL3
All Species:
27.88
Human Site:
T573
Identified Species:
61.33
UniProt:
Q9UH77
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UH77
NP_059111.2
587
64970
T573
L
L
P
T
N
M
S
T
G
R
S
Y
A
G
V
Chimpanzee
Pan troglodytes
XP_001169820
555
61472
T541
L
L
P
T
N
M
S
T
G
R
S
Y
A
G
V
Rhesus Macaque
Macaca mulatta
XP_001112192
587
64972
T573
L
L
P
T
N
M
S
T
G
R
S
Y
A
G
V
Dog
Lupus familis
XP_538644
718
78851
T571
L
L
P
T
N
M
S
T
G
R
S
Y
A
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZP3
593
65964
T579
V
V
S
S
C
M
S
T
G
R
S
Y
A
G
V
Rat
Rattus norvegicus
Q8K430
640
69714
R611
A
A
S
C
M
F
T
R
R
S
S
V
G
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_414621
586
65074
T572
L
L
P
T
S
M
S
T
G
R
S
Y
A
G
V
Frog
Xenopus laevis
Q6NRH0
564
63190
T551
A
V
V
T
S
M
A
T
Q
R
C
D
A
G
V
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
T551
E
V
V
T
S
M
A
T
Q
R
C
D
A
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q04652
1477
159964
I675
I
L
P
A
L
M
T
I
G
R
S
Y
A
G
V
Honey Bee
Apis mellifera
XP_393674
1049
117222
I601
T
L
P
T
C
M
G
I
G
R
S
Y
A
G
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
99.3
79.9
N.A.
76
43.2
N.A.
N.A.
94.5
39.5
39.5
N.A.
24.7
36.7
N.A.
N.A.
Protein Similarity:
100
94.5
99.4
80.9
N.A.
87.5
59.3
N.A.
N.A.
97.9
58.4
58.2
N.A.
31.7
45.7
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
66.6
6.6
N.A.
N.A.
93.3
46.6
46.6
N.A.
66.6
73.3
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
13.3
N.A.
N.A.
100
66.6
66.6
N.A.
80
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
10
0
0
19
0
0
0
0
0
91
0
10
% A
% Cys:
0
0
0
10
19
0
0
0
0
0
19
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
73
0
0
0
10
91
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
46
64
0
0
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
10
91
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
37
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
64
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
10
10
91
0
0
0
0
0
% R
% Ser:
0
0
19
10
28
0
55
0
0
10
82
0
0
0
0
% S
% Thr:
10
0
0
73
0
0
19
73
0
0
0
0
0
0
0
% T
% Val:
10
28
19
0
0
0
0
0
0
0
0
10
0
10
82
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _