KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLX
All Species:
14.24
Human Site:
Y149
Identified Species:
28.48
UniProt:
Q9UH92
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UH92
NP_733752.1
298
33300
Y149
R
D
A
I
K
R
G
Y
D
D
L
Q
T
I
V
Chimpanzee
Pan troglodytes
XP_001163510
268
30303
P127
D
D
L
Q
T
I
V
P
T
C
Q
Q
Q
D
F
Rhesus Macaque
Macaca mulatta
XP_001110337
298
33327
Y149
R
D
A
I
K
R
G
Y
D
D
L
Q
T
I
V
Dog
Lupus familis
XP_849377
298
33336
Y149
R
D
A
I
K
R
G
Y
D
D
L
Q
T
I
V
Cat
Felis silvestris
Mouse
Mus musculus
O08609
298
33320
Y149
R
D
A
I
K
R
G
Y
D
D
L
Q
T
I
V
Rat
Rattus norvegicus
P52164
160
18253
Q19
D
E
E
Q
P
R
F
Q
S
A
A
D
K
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P52162
160
18165
Q19
D
E
E
Q
P
R
F
Q
S
A
A
D
K
R
A
Frog
Xenopus laevis
Q07016
163
18666
A22
S
S
R
F
P
Y
S
A
D
K
R
A
H
H
N
Zebra Danio
Brachydanio rerio
NP_001019394
247
28134
T106
D
L
Q
S
I
V
P
T
C
Q
Q
Q
S
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651556
254
28941
K113
S
S
G
Y
K
L
S
K
A
L
I
L
Q
K
S
Honey Bee
Apis mellifera
XP_395909
245
27800
D104
K
G
Y
D
S
L
Q
D
L
V
P
T
C
Q
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793306
221
25127
P80
E
D
L
Q
L
I
V
P
T
C
Q
Q
P
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.9
98.6
95.3
N.A.
95.6
20.4
N.A.
N.A.
21.4
20.1
65.4
N.A.
35.9
51.3
N.A.
51
Protein Similarity:
100
89.9
98.9
96.3
N.A.
96.6
35.9
N.A.
N.A.
34.9
35.9
73.1
N.A.
54
63
N.A.
63
P-Site Identity:
100
13.3
100
100
N.A.
100
6.6
N.A.
N.A.
6.6
6.6
6.6
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
13.3
100
100
N.A.
100
13.3
N.A.
N.A.
13.3
6.6
13.3
N.A.
13.3
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
0
0
0
0
9
9
17
17
9
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
9
17
0
0
9
0
0
% C
% Asp:
34
50
0
9
0
0
0
9
42
34
0
17
0
25
0
% D
% Glu:
9
17
17
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
17
0
0
0
0
0
0
0
17
% F
% Gly:
0
9
9
0
0
0
34
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
9
% H
% Ile:
0
0
0
34
9
17
0
0
0
0
9
0
0
34
0
% I
% Lys:
9
0
0
0
42
0
0
9
0
9
0
0
17
9
0
% K
% Leu:
0
9
17
0
9
17
0
0
9
9
34
9
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
25
0
9
17
0
0
9
0
9
0
0
% P
% Gln:
0
0
9
34
0
0
9
17
0
9
25
59
17
9
9
% Q
% Arg:
34
0
9
0
0
50
0
0
0
0
9
0
0
17
0
% R
% Ser:
17
17
0
9
9
0
17
0
17
0
0
0
9
0
9
% S
% Thr:
0
0
0
0
9
0
0
9
17
0
0
9
34
0
0
% T
% Val:
0
0
0
0
0
9
17
0
0
9
0
0
0
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
9
0
9
0
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _