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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLH3
All Species:
12.42
Human Site:
S1442
Identified Species:
27.33
UniProt:
Q9UHC1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHC1
NP_001035197.1
1453
163712
S1442
A
E
C
D
T
R
Q
S
L
Q
Q
S
M
P
P
Chimpanzee
Pan troglodytes
XP_001158381
1451
163337
S1440
A
E
C
D
T
R
Q
S
L
Q
Q
S
M
P
P
Rhesus Macaque
Macaca mulatta
XP_001096911
1456
163780
S1445
A
E
C
D
T
T
Q
S
L
Q
Q
S
M
P
P
Dog
Lupus familis
XP_537511
1456
164697
S1445
E
R
C
N
T
R
Q
S
L
E
A
S
M
P
P
Cat
Felis silvestris
Mouse
Mus musculus
NP_780546
1411
158698
N1400
L
F
G
K
T
E
Q
N
L
Q
Q
P
I
R
P
Rat
Rattus norvegicus
NP_001101513
1442
161869
E1431
E
G
C
D
T
K
Q
E
P
Q
Q
P
V
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516394
973
102513
A963
T
A
G
G
T
T
S
A
A
G
L
P
P
S
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085796
1235
137921
P1225
Q
D
T
Q
P
T
S
P
K
K
V
A
T
Q
Q
Zebra Danio
Brachydanio rerio
XP_696739
1164
130422
G1154
Y
K
S
W
Q
L
Y
G
Q
N
Q
Y
F
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185665
1628
178951
E1611
S
T
V
N
E
N
K
E
R
Q
P
S
G
W
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195277
1155
129267
R1145
R
R
E
I
T
L
D
R
A
K
S
R
L
D
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
94.6
78.8
N.A.
70.4
71.5
N.A.
30.8
N.A.
37.2
37.2
N.A.
N.A.
N.A.
N.A.
24.1
Protein Similarity:
100
99.3
96.6
87.1
N.A.
79.5
80.3
N.A.
43.3
N.A.
53
54.9
N.A.
N.A.
N.A.
N.A.
43
P-Site Identity:
100
100
93.3
66.6
N.A.
40
53.3
N.A.
6.6
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
80
N.A.
53.3
66.6
N.A.
13.3
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
10
0
0
0
0
0
10
19
0
10
10
0
10
0
% A
% Cys:
0
0
46
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
37
0
0
10
0
0
0
0
0
0
10
0
% D
% Glu:
19
28
10
0
10
10
0
19
0
10
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
10
19
10
0
0
0
10
0
10
0
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
10
0
10
0
10
10
0
10
19
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
19
0
0
46
0
10
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
37
0
0
% M
% Asn:
0
0
0
19
0
10
0
10
0
10
0
0
0
0
10
% N
% Pro:
0
0
0
0
10
0
0
10
10
0
10
28
10
46
55
% P
% Gln:
10
0
0
10
10
0
55
0
10
55
55
0
0
10
19
% Q
% Arg:
10
19
0
0
0
28
0
10
10
0
0
10
0
10
0
% R
% Ser:
10
0
10
0
0
0
19
37
0
0
10
46
0
10
0
% S
% Thr:
10
10
10
0
73
28
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
10
0
10
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
10
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _