KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLH3
All Species:
15.45
Human Site:
T641
Identified Species:
34
UniProt:
Q9UHC1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHC1
NP_001035197.1
1453
163712
T641
G
P
T
R
A
Q
E
T
F
G
N
R
T
R
H
Chimpanzee
Pan troglodytes
XP_001158381
1451
163337
T641
G
P
T
R
A
Q
E
T
F
G
N
R
T
R
H
Rhesus Macaque
Macaca mulatta
XP_001096911
1456
163780
T644
G
P
T
R
A
Q
E
T
F
G
N
R
T
R
H
Dog
Lupus familis
XP_537511
1456
164697
T645
G
P
M
S
A
R
E
T
F
L
N
R
A
C
H
Cat
Felis silvestris
Mouse
Mus musculus
NP_780546
1411
158698
Y634
T
E
H
S
F
K
N
Y
A
R
P
G
P
V
S
Rat
Rattus norvegicus
NP_001101513
1442
161869
P633
L
F
K
N
Y
A
R
P
G
P
V
S
A
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516394
973
102513
A204
T
V
L
Q
L
P
K
A
K
D
V
R
A
R
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085796
1235
137921
S466
N
T
Q
P
A
A
T
S
Y
K
I
A
I
A
N
Zebra Danio
Brachydanio rerio
XP_696739
1164
130422
E395
E
A
C
E
T
M
I
E
K
N
D
S
S
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185665
1628
178951
S684
I
A
L
R
W
H
R
S
P
G
F
R
S
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_195277
1155
129267
F386
L
L
F
P
S
A
D
F
K
Q
D
G
D
Y
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
94.6
78.8
N.A.
70.4
71.5
N.A.
30.8
N.A.
37.2
37.2
N.A.
N.A.
N.A.
N.A.
24.1
Protein Similarity:
100
99.3
96.6
87.1
N.A.
79.5
80.3
N.A.
43.3
N.A.
53
54.9
N.A.
N.A.
N.A.
N.A.
43
P-Site Identity:
100
100
100
60
N.A.
0
0
N.A.
13.3
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
66.6
N.A.
6.6
6.6
N.A.
26.6
N.A.
26.6
13.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
46
28
0
10
10
0
0
10
28
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
10
19
0
10
0
0
% D
% Glu:
10
10
0
10
0
0
37
10
0
0
0
0
0
0
10
% E
% Phe:
0
10
10
0
10
0
0
10
37
0
10
0
0
0
19
% F
% Gly:
37
0
0
0
0
0
0
0
10
37
0
19
0
0
0
% G
% His:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
37
% H
% Ile:
10
0
0
0
0
0
10
0
0
0
10
0
10
0
0
% I
% Lys:
0
0
10
0
0
10
10
0
28
10
0
0
0
0
0
% K
% Leu:
19
10
19
0
10
0
0
0
0
10
0
0
0
0
10
% L
% Met:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
10
0
0
10
37
0
0
0
10
% N
% Pro:
0
37
0
19
0
10
0
10
10
10
10
0
10
0
0
% P
% Gln:
0
0
10
10
0
28
0
0
0
10
0
0
0
10
0
% Q
% Arg:
0
0
0
37
0
10
19
0
0
10
0
55
0
46
0
% R
% Ser:
0
0
0
19
10
0
0
19
0
0
0
19
19
0
10
% S
% Thr:
19
10
28
0
10
0
10
37
0
0
0
0
28
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
19
0
0
19
10
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
10
10
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _