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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MKRN1 All Species: 15.76
Human Site: S127 Identified Species: 28.89
UniProt: Q9UHC7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHC7 NP_038474.2 482 53349 S127 T E L T T K S S L A A S S S L
Chimpanzee Pan troglodytes XP_519424 482 53301 S127 T E L T T K S S L A A S S S L
Rhesus Macaque Macaca mulatta XP_001107668 445 50620 G102 S S L S S I V G P L V E M N T
Dog Lupus familis XP_851764 589 65699 S234 A D L T A K S S L A A S S S L
Cat Felis silvestris
Mouse Mus musculus Q9QXP6 481 52990 S127 T D L S A K P S L A A S S S L
Rat Rattus norvegicus NP_001004233 329 35029
Wallaby Macropus eugenll Q9TT91 478 52887 S127 A K S D L P A S S S L P A L V
Platypus Ornith. anatinus
Chicken Gallus gallus NP_990073 464 52212 Y121 V N P A A K T Y P S D L A L L
Frog Xenopus laevis Q6GLT5 408 45616 R64 S H D L A T S R S A M I C R Y
Zebra Danio Brachydanio rerio Q4VBT5 439 49681 G96 L T A A P L A G T P E P V S D
Tiger Blowfish Takifugu rubipres NP_001072050 429 48885 E80 C K P T K S E E V S N P Q M L
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783167 572 64160 K135 M K D L I H A K E F V P G Q P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6IDS6 323 36544
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 89.4 75.8 N.A. 93.7 62.8 86.7 N.A. 74.6 59.7 63.6 61.2 N.A. N.A. N.A. 35.8
Protein Similarity: 100 99.7 90 77.4 N.A. 95.4 63.6 91.2 N.A. 80.7 67.2 75.3 73.2 N.A. N.A. N.A. 48.6
P-Site Identity: 100 100 6.6 80 N.A. 73.3 0 6.6 N.A. 13.3 13.3 6.6 13.3 N.A. N.A. N.A. 0
P-Site Similarity: 100 100 33.3 86.6 N.A. 86.6 0 40 N.A. 33.3 20 13.3 33.3 N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 28 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 8 16 31 0 24 0 0 39 31 0 16 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 16 16 8 0 0 0 0 0 0 8 0 0 0 8 % D
% Glu: 0 16 0 0 0 0 8 8 8 0 8 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 16 0 0 0 0 8 0 0 % G
% His: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 8 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 24 0 0 8 39 0 8 0 0 0 0 0 0 0 % K
% Leu: 8 0 39 16 8 8 0 0 31 8 8 8 0 16 47 % L
% Met: 8 0 0 0 0 0 0 0 0 0 8 0 8 8 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 8 0 0 8 0 % N
% Pro: 0 0 16 0 8 8 8 0 16 8 0 31 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % R
% Ser: 16 8 8 16 8 8 31 39 16 24 0 31 31 39 0 % S
% Thr: 24 8 0 31 16 8 8 0 8 0 0 0 0 0 8 % T
% Val: 8 0 0 0 0 0 8 0 8 0 16 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _