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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEPT9 All Species: 13.03
Human Site: T518 Identified Species: 35.83
UniProt: Q9UHD8 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHD8 NP_001106963.1 586 65401 T518 K R I L G R K T K W G T I E V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001102088 360 40906 L301 L N H C E F A L L R D F V I R
Dog Lupus familis XP_540458 602 66902 T534 G R K T K W G T I E A P H W A
Cat Felis silvestris
Mouse Mus musculus Q80UG5 583 65556 T516 K R I L G R K T K W G T I E V
Rat Rattus norvegicus Q9QZR6 564 63773 T497 K R I L G R K T K W G T I E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505764 436 49083 H377 I E V E N T T H C E F A Y L R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2BGU8 361 40623 N302 W G V V E V E N P N H C E F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795119 662 73144 T601 R E I L G R L T N W G L I E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25342 322 37006 I263 S A I N V E D I N Q C D F V Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 42.4 85.5 N.A. 90 85.8 N.A. 60.5 N.A. N.A. 41.1 N.A. N.A. N.A. N.A. 37.7
Protein Similarity: 100 N.A. 50.6 89.3 N.A. 94 89.7 N.A. 66.7 N.A. N.A. 50.6 N.A. N.A. N.A. N.A. 53.9
P-Site Identity: 100 N.A. 0 13.3 N.A. 100 100 N.A. 0 N.A. N.A. 0 N.A. N.A. N.A. N.A. 66.6
P-Site Similarity: 100 N.A. 6.6 13.3 N.A. 100 100 N.A. 6.6 N.A. N.A. 20 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 38 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 12 0 0 0 12 12 0 0 12 % A
% Cys: 0 0 0 12 0 0 0 0 12 0 12 12 0 0 0 % C
% Asp: 0 0 0 0 0 0 12 0 0 0 12 12 0 0 0 % D
% Glu: 0 23 0 12 23 12 12 0 0 23 0 0 12 45 0 % E
% Phe: 0 0 0 0 0 12 0 0 0 0 12 12 12 12 0 % F
% Gly: 12 12 0 0 45 0 12 0 0 0 45 0 0 0 0 % G
% His: 0 0 12 0 0 0 0 12 0 0 12 0 12 0 0 % H
% Ile: 12 0 56 0 0 0 0 12 12 0 0 0 45 12 0 % I
% Lys: 34 0 12 0 12 0 34 0 34 0 0 0 0 0 0 % K
% Leu: 12 0 0 45 0 0 12 12 12 0 0 12 0 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 0 12 12 0 0 12 23 12 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 12 0 0 12 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % Q
% Arg: 12 45 0 0 0 45 0 0 0 12 0 0 0 0 23 % R
% Ser: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % S
% Thr: 0 0 0 12 0 12 12 56 0 0 0 34 0 0 0 % T
% Val: 0 0 23 12 12 12 0 0 0 0 0 0 12 12 45 % V
% Trp: 12 0 0 0 0 12 0 0 0 45 0 0 0 12 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _