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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STEAP1
All Species:
26.36
Human Site:
S244
Identified Species:
64.44
UniProt:
Q9UHE8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHE8
NP_036581.1
339
39851
S244
S
I
P
S
V
S
D
S
L
T
W
R
E
F
H
Chimpanzee
Pan troglodytes
XP_001164838
339
39774
S244
S
I
P
S
V
S
D
S
L
T
W
R
E
F
H
Rhesus Macaque
Macaca mulatta
XP_001103524
339
39848
S244
S
I
P
S
V
S
D
S
L
T
W
R
E
F
H
Dog
Lupus familis
XP_532454
339
40064
S244
S
I
P
S
V
S
D
S
L
T
W
R
E
F
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWR7
339
39274
S244
S
I
P
S
V
S
D
S
L
T
W
R
E
F
H
Rat
Rattus norvegicus
Q5RKL5
488
54655
S385
S
I
P
S
I
A
N
S
L
N
W
K
E
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510572
489
55412
A385
S
I
P
S
V
S
S
A
L
N
W
R
E
F
S
Chicken
Gallus gallus
XP_418642
342
40232
S247
S
I
P
S
V
S
H
S
L
T
W
R
E
F
H
Frog
Xenopus laevis
NP_001083586
474
53302
A373
S
L
P
S
V
S
N
A
V
N
W
R
E
F
R
Zebra Danio
Brachydanio rerio
XP_001921185
492
55634
A388
S
I
P
S
V
H
D
A
L
N
W
R
E
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
90.5
N.A.
82
35
N.A.
34.1
65.1
32.2
31.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
99.1
95.8
N.A.
89.9
49.3
N.A.
50
80.6
48.5
50.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
60
N.A.
73.3
93.3
60
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
86.6
N.A.
80
93.3
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
30
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
60
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
60
% H
% Ile:
0
90
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
90
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
20
0
0
40
0
0
0
0
0
% N
% Pro:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
90
0
0
10
% R
% Ser:
100
0
0
100
0
80
10
70
0
0
0
0
0
0
30
% S
% Thr:
0
0
0
0
0
0
0
0
0
60
0
0
0
0
0
% T
% Val:
0
0
0
0
90
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _