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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NAT8B
All Species:
4.85
Human Site:
S12
Identified Species:
13.33
UniProt:
Q9UHF3
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHF3
NP_057431.2
227
25366
S12
H
I
R
K
Y
Q
E
S
D
R
K
S
V
V
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105263
227
25639
S12
H
I
R
K
Y
Q
E
S
D
R
K
W
V
V
R
Dog
Lupus familis
XP_540227
302
33307
R80
H
I
R
K
Y
Q
E
R
D
R
P
R
V
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIY7
227
25620
R12
R
I
R
Q
F
Q
E
R
D
Y
K
Q
V
V
D
Rat
Rattus norvegicus
P85118
226
25484
R12
H
I
R
Q
F
Q
D
R
D
H
R
R
V
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516486
223
25625
E11
F
R
I
R
R
Y
R
E
E
D
F
E
A
V
W
Chicken
Gallus gallus
XP_427317
219
24176
Frog
Xenopus laevis
Q9I8W5
219
25047
Zebra Danio
Brachydanio rerio
A4IGD2
282
32252
S50
A
S
P
S
A
L
E
S
K
I
E
K
R
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.2
47.6
N.A.
61.6
53.7
N.A.
51
40.9
34.7
26.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
88.9
56.9
N.A.
71.3
67.8
N.A.
66.9
59.4
53.2
46.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
86.6
66.6
N.A.
53.3
40
N.A.
6.6
0
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
86.6
73.3
N.A.
66.6
73.3
N.A.
20
0
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
56
12
0
0
0
0
34
% D
% Glu:
0
0
0
0
0
0
56
12
12
0
12
12
0
0
0
% E
% Phe:
12
0
0
0
23
0
0
0
0
0
12
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
45
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
56
12
0
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
0
34
0
0
0
0
12
0
34
12
0
0
0
% K
% Leu:
0
0
0
0
0
12
0
0
0
0
0
0
0
23
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% P
% Gln:
0
0
0
23
0
56
0
0
0
0
0
12
0
0
12
% Q
% Arg:
12
12
56
12
12
0
12
34
0
34
12
23
12
0
12
% R
% Ser:
0
12
0
12
0
0
0
34
0
0
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
56
45
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% W
% Tyr:
0
0
0
0
34
12
0
0
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _