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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NAT8B All Species: 7.88
Human Site: Y9 Identified Species: 21.67
UniProt: Q9UHF3 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHF3 NP_057431.2 227 25366 Y9 A P Y H I R K Y Q E S D R K S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105263 227 25639 Y9 A P Y H I R K Y Q E S D R K W
Dog Lupus familis XP_540227 302 33307 Y77 A P Y H I R K Y Q E R D R P R
Cat Felis silvestris
Mouse Mus musculus Q9JIY7 227 25620 F9 A S F R I R Q F Q E R D Y K Q
Rat Rattus norvegicus P85118 226 25484 F9 A P Y H I R Q F Q D R D H R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516486 223 25625 R8 M A H F R I R R Y R E E D F E
Chicken Gallus gallus XP_427317 219 24176
Frog Xenopus laevis Q9I8W5 219 25047
Zebra Danio Brachydanio rerio A4IGD2 282 32252 A47 S S S A S P S A L E S K I E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 83.2 47.6 N.A. 61.6 53.7 N.A. 51 40.9 34.7 26.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 88.9 56.9 N.A. 71.3 67.8 N.A. 66.9 59.4 53.2 46.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 93.3 80 N.A. 46.6 53.3 N.A. 0 0 0 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 93.3 80 N.A. 66.6 80 N.A. 20 0 0 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 56 12 0 12 0 0 0 12 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 12 0 56 12 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 56 12 12 0 12 12 % E
% Phe: 0 0 12 12 0 0 0 23 0 0 0 0 0 12 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 12 45 0 0 0 0 0 0 0 0 12 0 0 % H
% Ile: 0 0 0 0 56 12 0 0 0 0 0 0 12 0 0 % I
% Lys: 0 0 0 0 0 0 34 0 0 0 0 12 0 34 12 % K
% Leu: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % L
% Met: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 45 0 0 0 12 0 0 0 0 0 0 0 12 0 % P
% Gln: 0 0 0 0 0 0 23 0 56 0 0 0 0 0 12 % Q
% Arg: 0 0 0 12 12 56 12 12 0 12 34 0 34 12 23 % R
% Ser: 12 23 12 0 12 0 12 0 0 0 34 0 0 0 12 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % W
% Tyr: 0 0 45 0 0 0 0 34 12 0 0 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _