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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYOX1
All Species:
18.18
Human Site:
S273
Identified Species:
40
UniProt:
Q9UHG3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHG3
NP_057381.3
505
56640
S273
K
S
N
L
I
S
G
S
V
M
Y
I
E
E
K
Chimpanzee
Pan troglodytes
XP_001163338
494
54628
I262
K
L
T
K
A
N
V
I
H
A
T
V
T
S
V
Rhesus Macaque
Macaca mulatta
XP_001098650
508
57050
S276
K
S
N
L
I
S
G
S
V
I
Y
I
E
E
K
Dog
Lupus familis
XP_538538
505
56687
S273
R
S
N
L
I
A
G
S
V
L
Y
I
E
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQF9
505
56476
S273
S
S
N
L
I
S
G
S
V
M
S
I
E
E
K
Rat
Rattus norvegicus
Q99ML5
504
56269
G272
S
N
S
N
L
I
S
G
S
V
M
S
I
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518320
497
54467
I265
K
L
T
K
A
N
V
I
K
A
K
V
T
D
V
Chicken
Gallus gallus
XP_423959
502
56048
T270
K
A
D
V
I
A
G
T
V
V
S
I
E
P
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017626
509
56654
R273
K
A
E
V
V
P
A
R
V
T
A
I
S
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787222
504
55960
K273
L
L
Q
R
S
G
A
K
L
M
K
S
R
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P57681
500
55280
S267
G
S
G
G
G
L
W
S
V
E
G
G
N
W
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.9
91.1
85.3
N.A.
78.8
77.4
N.A.
43.7
60.2
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
37.6
Protein Similarity:
100
63.1
92.9
93.6
N.A.
89.6
88.5
N.A.
61.5
74
N.A.
65.8
N.A.
N.A.
N.A.
N.A.
57.2
P-Site Identity:
100
6.6
93.3
80
N.A.
86.6
13.3
N.A.
6.6
46.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
100
100
N.A.
86.6
40
N.A.
26.6
86.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
19
19
19
0
0
19
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
10
0
0
46
46
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
10
10
10
10
46
10
0
0
10
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
46
10
0
19
0
10
0
55
10
0
0
% I
% Lys:
55
0
0
19
0
0
0
10
10
0
19
0
0
0
64
% K
% Leu:
10
28
0
37
10
10
0
0
10
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
28
10
0
0
10
0
% M
% Asn:
0
10
37
10
0
19
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
0
0
10
0
0
0
10
0
0
0
0
10
0
0
% R
% Ser:
19
46
10
0
10
28
10
46
10
0
19
19
10
10
0
% S
% Thr:
0
0
19
0
0
0
0
10
0
10
10
0
19
0
0
% T
% Val:
0
0
0
19
10
0
19
0
64
19
0
19
0
10
19
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
28
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _