KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYOX1
All Species:
21.21
Human Site:
Y498
Identified Species:
46.67
UniProt:
Q9UHG3
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHG3
NP_057381.3
505
56640
Y498
M
I
D
Q
D
G
L
Y
E
K
L
K
T
E
L
Chimpanzee
Pan troglodytes
XP_001163338
494
54628
M487
K
I
D
Q
K
D
L
M
H
K
V
K
T
E
L
Rhesus Macaque
Macaca mulatta
XP_001098650
508
57050
Y501
M
I
D
Q
D
G
L
Y
E
K
L
K
T
E
L
Dog
Lupus familis
XP_538538
505
56687
Y498
M
I
D
Q
E
D
L
Y
E
K
L
K
T
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQF9
505
56476
Y498
M
I
D
Q
D
D
L
Y
E
R
L
K
T
E
L
Rat
Rattus norvegicus
Q99ML5
504
56269
Y497
M
I
D
Q
D
D
L
Y
E
K
L
K
T
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518320
497
54467
L490
K
I
D
Q
K
D
L
L
H
K
V
K
T
E
L
Chicken
Gallus gallus
XP_423959
502
56048
Y495
K
I
D
Q
E
D
L
Y
E
K
L
K
T
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001017626
509
56654
Q498
E
Q
T
A
K
I
D
Q
E
D
L
H
T
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_787222
504
55960
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P57681
500
55280
C492
S
S
S
D
K
R
S
C
S
S
G
L
H
S
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.9
91.1
85.3
N.A.
78.8
77.4
N.A.
43.7
60.2
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
37.6
Protein Similarity:
100
63.1
92.9
93.6
N.A.
89.6
88.5
N.A.
61.5
74
N.A.
65.8
N.A.
N.A.
N.A.
N.A.
57.2
P-Site Identity:
100
60
100
86.6
N.A.
86.6
93.3
N.A.
60
80
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
66.6
100
93.3
N.A.
93.3
93.3
N.A.
66.6
86.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
73
10
37
55
10
0
0
10
0
0
0
0
10
% D
% Glu:
10
0
0
0
19
0
0
0
64
0
0
0
0
73
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
19
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
19
0
0
10
10
0
0
% H
% Ile:
0
73
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
28
0
0
0
37
0
0
0
0
64
0
73
0
0
0
% K
% Leu:
0
0
0
0
0
0
73
10
0
0
64
10
0
0
82
% L
% Met:
46
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
73
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
10
0
0
0
10
0
% R
% Ser:
10
10
10
0
0
0
10
0
10
10
0
0
0
10
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
82
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _