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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IP6K2
All Species:
14.55
Human Site:
T418
Identified Species:
40
UniProt:
Q9UHH9
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHH9
NP_001005909.1
426
49186
T418
Q
S
L
I
D
I
V
T
E
I
S
E
E
S
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001107338
441
50213
Y422
H
D
G
P
D
R
G
Y
V
F
G
L
E
N
L
Dog
Lupus familis
XP_851186
425
48942
T417
Q
S
L
I
D
I
V
T
E
I
S
E
E
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80V72
448
51607
T440
Q
S
L
I
D
I
V
T
E
I
S
E
E
S
G
Rat
Rattus norvegicus
Q9R0U1
425
49145
T417
Q
S
L
I
D
I
V
T
E
I
S
E
E
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509782
405
46287
L398
L
E
N
L
I
R
I
L
R
D
I
A
E
G
K
Chicken
Gallus gallus
NP_001025767
424
49350
E417
N
L
I
D
I
I
K
E
I
R
D
E
N
S
E
Frog
Xenopus laevis
NP_001086213
429
49627
I417
I
F
G
L
Q
N
L
I
A
I
I
K
E
I
R
Zebra Danio
Brachydanio rerio
NP_958878
463
52406
V416
D
S
G
P
A
V
D
V
R
M
I
D
F
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
49.2
97.1
N.A.
91.7
96.2
N.A.
44.1
85.6
78.7
61.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
65
97.8
N.A.
93.3
98.1
N.A.
62.6
92.4
88.8
73.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
6.6
20
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
20
100
N.A.
100
100
N.A.
20
26.6
33.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
0
0
12
0
0
12
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
0
12
56
0
12
0
0
12
12
12
0
0
0
% D
% Glu:
0
12
0
0
0
0
0
12
45
0
0
56
78
0
12
% E
% Phe:
0
12
0
0
0
0
0
0
0
12
0
0
12
0
0
% F
% Gly:
0
0
34
0
0
0
12
0
0
0
12
0
0
12
45
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
12
0
12
45
23
56
12
12
12
56
34
0
0
12
0
% I
% Lys:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
12
% K
% Leu:
12
12
45
23
0
0
12
12
0
0
0
12
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
12
0
12
0
0
12
0
0
0
0
0
0
12
12
0
% N
% Pro:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
45
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
23
0
0
23
12
0
0
0
0
12
% R
% Ser:
0
56
0
0
0
0
0
0
0
0
45
0
0
56
0
% S
% Thr:
0
0
0
0
0
0
0
45
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
12
45
12
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _