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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A8
All Species:
12.42
Human Site:
S502
Identified Species:
24.85
UniProt:
Q9UHI5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHI5
NP_036376.2
535
58382
S502
Y
P
E
V
E
R
G
S
G
T
E
E
A
N
E
Chimpanzee
Pan troglodytes
XP_001161667
533
57970
S500
Y
P
E
V
E
R
G
S
G
T
E
E
A
N
E
Rhesus Macaque
Macaca mulatta
XP_001106706
535
58272
S502
Y
P
E
A
E
Q
G
S
G
T
E
K
A
N
E
Dog
Lupus familis
XP_547730
532
58192
S502
Y
P
E
M
D
A
G
S
R
T
E
E
T
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXW9
531
57855
G501
Y
P
Q
E
G
N
S
G
A
E
E
T
T
D
D
Rat
Rattus norvegicus
Q9WVR6
533
58172
G503
Y
P
Q
E
G
D
S
G
T
E
E
T
I
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509274
498
54814
V468
W
G
Q
K
L
C
F
V
V
Y
P
H
E
G
A
Chicken
Gallus gallus
B3TP03
654
71198
D614
E
G
R
H
S
D
G
D
G
D
S
C
S
E
N
Frog
Xenopus laevis
A1L3M3
510
55983
F481
F
I
S
K
I
L
A
F
L
T
R
W
T
Q
M
Zebra Danio
Brachydanio rerio
Q59I64
468
51216
P439
H
L
P
E
S
K
R
P
P
I
I
T
K
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790356
509
55459
K480
F
L
C
V
W
Y
K
K
K
P
L
F
I
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50276
574
63203
K541
F
W
R
V
K
I
A
K
V
Y
D
D
T
I
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98.6
93.4
N.A.
91.5
91.9
N.A.
64.1
22.6
44.4
45.9
N.A.
N.A.
N.A.
N.A.
48.7
Protein Similarity:
100
98.8
99.4
96.2
N.A.
95.3
95.3
N.A.
76.2
40.8
65
63.9
N.A.
N.A.
N.A.
N.A.
66.5
P-Site Identity:
100
100
80
66.6
N.A.
20
20
N.A.
0
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
80
N.A.
40
40
N.A.
13.3
20
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
17
0
9
0
0
0
25
0
9
% A
% Cys:
0
0
9
0
0
9
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
9
17
0
9
0
9
9
9
0
17
17
% D
% Glu:
9
0
34
25
25
0
0
0
0
17
50
25
9
9
34
% E
% Phe:
25
0
0
0
0
0
9
9
0
0
0
9
0
0
0
% F
% Gly:
0
17
0
0
17
0
42
17
34
0
0
0
0
9
9
% G
% His:
9
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
9
0
0
9
9
0
0
0
9
9
0
17
9
0
% I
% Lys:
0
0
0
17
9
9
9
17
9
0
0
9
9
0
0
% K
% Leu:
0
17
0
0
9
9
0
0
9
0
9
0
0
17
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
0
34
17
% N
% Pro:
0
50
9
0
0
0
0
9
9
9
9
0
0
0
0
% P
% Gln:
0
0
25
0
0
9
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
17
0
0
17
9
0
9
0
9
0
0
0
0
% R
% Ser:
0
0
9
0
17
0
17
34
0
0
9
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
42
0
25
34
0
0
% T
% Val:
0
0
0
34
0
0
0
9
17
0
0
0
0
0
0
% V
% Trp:
9
9
0
0
9
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
50
0
0
0
0
9
0
0
0
17
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _