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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A8
All Species:
29.39
Human Site:
Y107
Identified Species:
58.79
UniProt:
Q9UHI5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHI5
NP_036376.2
535
58382
Y107
I
P
K
S
G
G
D
Y
S
Y
V
K
D
I
F
Chimpanzee
Pan troglodytes
XP_001161667
533
57970
Y107
I
P
K
S
G
G
D
Y
S
Y
V
K
D
I
F
Rhesus Macaque
Macaca mulatta
XP_001106706
535
58272
Y107
I
P
K
S
G
G
D
Y
S
Y
V
K
D
I
F
Dog
Lupus familis
XP_547730
532
58192
Y107
I
P
K
S
G
G
D
Y
S
Y
V
K
D
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXW9
531
57855
Y106
I
P
K
S
G
G
D
Y
S
Y
V
K
D
I
F
Rat
Rattus norvegicus
Q9WVR6
533
58172
Y108
I
P
K
S
G
G
D
Y
S
Y
V
K
D
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509274
498
54814
I104
L
L
W
S
A
V
L
I
M
Y
P
T
S
L
A
Chicken
Gallus gallus
B3TP03
654
71198
W110
Y
V
A
V
G
E
L
W
A
F
I
T
G
W
N
Frog
Xenopus laevis
A1L3M3
510
55983
Y107
I
K
K
S
G
A
S
Y
A
Y
I
L
E
A
F
Zebra Danio
Brachydanio rerio
Q59I64
468
51216
A86
E
S
F
G
G
F
I
A
F
I
R
L
W
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790356
509
55459
Y118
I
P
K
S
G
G
E
Y
A
Y
I
M
A
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50276
574
63203
K128
I
P
K
N
G
G
E
K
N
Y
L
E
A
I
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
98.6
93.4
N.A.
91.5
91.9
N.A.
64.1
22.6
44.4
45.9
N.A.
N.A.
N.A.
N.A.
48.7
Protein Similarity:
100
98.8
99.4
96.2
N.A.
95.3
95.3
N.A.
76.2
40.8
65
63.9
N.A.
N.A.
N.A.
N.A.
66.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
6.6
46.6
6.6
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
33.3
66.6
6.6
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
9
0
9
25
0
0
0
17
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
50
0
0
0
0
0
50
0
0
% D
% Glu:
9
0
0
0
0
9
17
0
0
0
0
9
9
0
0
% E
% Phe:
0
0
9
0
0
9
0
0
9
9
0
0
0
0
75
% F
% Gly:
0
0
0
9
92
67
0
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
75
0
0
0
0
0
9
9
0
9
25
0
0
59
0
% I
% Lys:
0
9
75
0
0
0
0
9
0
0
0
50
0
0
0
% K
% Leu:
9
9
0
0
0
0
17
0
0
0
9
17
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
9
% N
% Pro:
0
67
0
0
0
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
9
0
75
0
0
9
0
50
0
0
0
9
9
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
17
0
9
0
% T
% Val:
0
9
0
9
0
9
0
0
0
0
50
0
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
9
0
0
0
0
9
9
0
% W
% Tyr:
9
0
0
0
0
0
0
67
0
84
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _