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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SHPK All Species: 17.88
Human Site: S391 Identified Species: 49.17
UniProt: Q9UHJ6 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHJ6 NP_037408.2 478 51491 S391 S V T R I S S S D L S L G H V
Chimpanzee Pan troglodytes XP_523551 478 51413 S391 S V T R I S S S D L S L G H V
Rhesus Macaque Macaca mulatta XP_001117628 274 29261 Y204 Q N A A S W G Y F N T Q S Q R
Dog Lupus familis XP_548339 472 50726 S385 S V T R I S S S D L T L G H V
Cat Felis silvestris
Mouse Mus musculus Q9D5J6 476 51284 S389 S V T R I S S S D L S L G H V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415852 470 50841 S389 S V A S I A A S E L S L G H V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001341627 454 48794 V384 L G H V T R A V C R G I I E N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_499810 435 47936 E365 D D P L Q L L E A T H Q G I I
Sea Urchin Strong. purpuratus XP_790539 480 52150 E398 T V S N V C F E N L S L G D V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 53.5 86.6 N.A. 87 N.A. N.A. N.A. 64.2 N.A. 51.2 N.A. N.A. N.A. 27.4 44.3
Protein Similarity: 100 99.7 55.6 91.6 N.A. 92.4 N.A. N.A. N.A. 79.9 N.A. 67.3 N.A. N.A. N.A. 43.5 62.5
P-Site Identity: 100 100 0 93.3 N.A. 100 N.A. N.A. N.A. 66.6 N.A. 0 N.A. N.A. N.A. 6.6 40
P-Site Similarity: 100 100 6.6 100 N.A. 100 N.A. N.A. N.A. 86.6 N.A. 13.3 N.A. N.A. N.A. 13.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 23 12 0 12 23 0 12 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 12 0 0 12 0 0 0 0 0 0 % C
% Asp: 12 12 0 0 0 0 0 0 45 0 0 0 0 12 0 % D
% Glu: 0 0 0 0 0 0 0 23 12 0 0 0 0 12 0 % E
% Phe: 0 0 0 0 0 0 12 0 12 0 0 0 0 0 0 % F
% Gly: 0 12 0 0 0 0 12 0 0 0 12 0 78 0 0 % G
% His: 0 0 12 0 0 0 0 0 0 0 12 0 0 56 0 % H
% Ile: 0 0 0 0 56 0 0 0 0 0 0 12 12 12 12 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 12 0 0 12 0 12 12 0 0 67 0 67 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 12 0 12 0 0 0 0 12 12 0 0 0 0 12 % N
% Pro: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 12 0 0 0 12 0 0 0 0 0 0 23 0 12 0 % Q
% Arg: 0 0 0 45 0 12 0 0 0 12 0 0 0 0 12 % R
% Ser: 56 0 12 12 12 45 45 56 0 0 56 0 12 0 0 % S
% Thr: 12 0 45 0 12 0 0 0 0 12 23 0 0 0 0 % T
% Val: 0 67 0 12 12 0 0 12 0 0 0 0 0 0 67 % V
% Trp: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _