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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMACR All Species: 12.12
Human Site: S115 Identified Species: 22.22
UniProt: Q9UHK6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHK6 NP_055139.4 382 42360 S115 S G F G Q S G S F C R L A G H
Chimpanzee Pan troglodytes XP_001152698 382 42384 S115 S G F G Q S G S F S W L A G H
Rhesus Macaque Macaca mulatta XP_001088403 382 42109 S115 T G F G Q S G S F S R L A G H
Dog Lupus familis XP_855429 382 41810 R115 S G F G Q S G R F S K T A G H
Cat Felis silvestris
Mouse Mus musculus O09174 381 41700 I114 S G F G Q S G I F S K V A G H
Rat Rattus norvegicus P70473 382 41810 I115 S G F G Q S G I F S K V A G H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026619 383 41722 K116 T G F G Q T G K Y A K S A G H
Frog Xenopus laevis NP_001167512 381 41146 K115 T G F G Q S G K Y A K A A G H
Zebra Danio Brachydanio rerio NP_001018462 382 41394 S115 T G Y G Q S G S Y A K A A G H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610054 373 41594 R114 T G F G Q H G R L A Q R A G H
Honey Bee Apis mellifera XP_395802 380 42448 P116 T G F G Q N G P Y A N M A G H
Nematode Worm Caenorhab. elegans Q09618 340 37713 G90 P G T L E K M G L D P S T L W
Sea Urchin Strong. purpuratus XP_794568 384 41379 P116 S G F G Q E G P L K H I A G H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 92.6 80.6 N.A. 77.2 77.7 N.A. N.A. 71.2 63.3 62.8 N.A. 49.7 49.7 38.7 54.9
Protein Similarity: 100 99.2 96.3 90.8 N.A. 88.2 89 N.A. N.A. 85.9 79.5 81.1 N.A. 65.7 70.6 55.2 71.8
P-Site Identity: 100 86.6 86.6 73.3 N.A. 73.3 73.3 N.A. N.A. 53.3 60 60 N.A. 53.3 53.3 6.6 60
P-Site Similarity: 100 86.6 93.3 80 N.A. 86.6 86.6 N.A. N.A. 80 80 86.6 N.A. 66.6 80 13.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 39 0 16 93 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 85 0 0 0 0 0 47 0 0 0 0 0 0 % F
% Gly: 0 100 0 93 0 0 93 8 0 0 0 0 0 93 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 93 % H
% Ile: 0 0 0 0 0 0 0 16 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 8 0 16 0 8 47 0 0 0 0 % K
% Leu: 0 0 0 8 0 0 0 0 24 0 0 24 0 8 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % N
% Pro: 8 0 0 0 0 0 0 16 0 0 8 0 0 0 0 % P
% Gln: 0 0 0 0 93 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 16 0 0 16 8 0 0 0 % R
% Ser: 47 0 0 0 0 62 0 31 0 39 0 16 0 0 0 % S
% Thr: 47 0 8 0 0 8 0 0 0 0 0 8 8 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % W
% Tyr: 0 0 8 0 0 0 0 0 31 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _