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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMACR
All Species:
28.18
Human Site:
S339
Identified Species:
51.67
UniProt:
Q9UHK6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHK6
NP_055139.4
382
42360
S339
L
N
T
P
A
I
P
S
F
K
R
D
P
F
I
Chimpanzee
Pan troglodytes
XP_001152698
382
42384
S339
L
N
T
P
A
I
P
S
F
K
R
D
P
F
V
Rhesus Macaque
Macaca mulatta
XP_001088403
382
42109
S339
S
N
T
P
A
I
P
S
F
K
R
D
P
F
V
Dog
Lupus familis
XP_855429
382
41810
S339
S
G
T
P
A
V
P
S
C
K
R
N
P
F
V
Cat
Felis silvestris
Mouse
Mus musculus
O09174
381
41700
S338
S
R
T
P
A
V
P
S
A
K
R
D
P
S
V
Rat
Rattus norvegicus
P70473
382
41810
S339
S
R
T
P
A
V
P
S
A
K
R
D
P
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026619
383
41722
S340
S
R
T
P
A
V
P
S
C
K
R
D
P
F
I
Frog
Xenopus laevis
NP_001167512
381
41146
T338
S
R
T
P
A
A
P
T
S
S
R
D
P
L
V
Zebra Danio
Brachydanio rerio
NP_001018462
382
41394
C339
S
R
S
P
A
E
P
C
G
S
R
D
P
F
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610054
373
41594
T330
P
A
P
V
L
S
R
T
P
G
K
L
P
K
A
Honey Bee
Apis mellifera
XP_395802
380
42448
K336
S
R
T
P
G
I
S
K
K
Y
Q
K
I
P
E
Nematode Worm
Caenorhab. elegans
Q09618
340
37713
I297
C
V
T
P
V
L
D
I
H
E
V
G
S
Y
G
Sea Urchin
Strong. purpuratus
XP_794568
384
41379
S341
S
R
T
P
G
S
P
S
T
M
A
L
P
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
92.6
80.6
N.A.
77.2
77.7
N.A.
N.A.
71.2
63.3
62.8
N.A.
49.7
49.7
38.7
54.9
Protein Similarity:
100
99.2
96.3
90.8
N.A.
88.2
89
N.A.
N.A.
85.9
79.5
81.1
N.A.
65.7
70.6
55.2
71.8
P-Site Identity:
100
93.3
86.6
60
N.A.
60
60
N.A.
N.A.
73.3
46.6
53.3
N.A.
6.6
20
13.3
33.3
P-Site Similarity:
100
100
93.3
80
N.A.
73.3
73.3
N.A.
N.A.
80
60
60
N.A.
20
26.6
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
70
8
0
0
16
0
8
0
0
8
8
% A
% Cys:
8
0
0
0
0
0
0
8
16
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
62
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
24
0
0
0
0
47
0
% F
% Gly:
0
8
0
0
16
0
0
0
8
8
0
8
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
31
0
8
0
0
0
0
8
0
24
% I
% Lys:
0
0
0
0
0
0
0
8
8
54
8
8
0
8
0
% K
% Leu:
16
0
0
0
8
8
0
0
0
0
0
16
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
24
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
0
8
93
0
0
77
0
8
0
0
0
85
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
54
0
0
0
0
8
0
0
0
70
0
0
0
0
% R
% Ser:
70
0
8
0
0
16
8
62
8
16
0
0
8
16
0
% S
% Thr:
0
0
85
0
0
0
0
16
8
0
0
0
0
0
0
% T
% Val:
0
8
0
8
8
31
0
0
0
0
8
0
0
0
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _